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nicastrin antibody | antibody review based on formal publications
NCSTN antibodies
This is a review about nicastrin antibodies, based on 7 published articles using nicastrin antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited nicastrin antibody.
Sigma-Aldrich    search Sigma-Aldrich NCSTN products
ip, wbSigma rabbit polyclonal anti-Nct antibody was used in western blot and immunoprecipitation to detect Nct in the purified gamma-secretase complex from detergent-solubilized HeLa cell membranes. to the paper
wbSigma polyclonal anti-nicastrin (N1660) was used in Western blot to study the biological function of presenilin-1 maturation. to the paper
wbSigma rabbit polyclonal Nct antibody N1660 was used in Western blot to study the biological function of Gamma-secretase. to the paper
wbSigma anti-nicastrin antibody was used in western blot to study intermolecular interactions and function of presenilin complexes. to the paper
wbSigma anti-NCT antibody (N1660) that recognizes the C terminus of NCT was used in western blot to study distinct gamma-secretase complexes composed of the known subunits in human cells. to the paper
wbSigma anti-Nct polyclonal antibody was used in immunohistochemistry to study the PEN-2 as an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin. to the paper
AFFINITY BIOREAGENTS
wbAffinity Bioreagents polyclonal antibody anti-nicastrin (PA1-758) was used in Western blot to study the biological function of APH-1 in maturation of presenilin-nicastrin complexes. to the paper
Articles Reviewed
1:Jay H Chyung et al. Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage. 2005
2:Shuxia Zhou et al. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production. 2005
3:Yoshifumi Nakaya et al. Random mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides. 2005
4:Hiroshi Hasegawa et al. Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes. 2004
5:Keiro Shirotani et al. Identification of distinct gamma-secretase complexes with different APH-1 variants. 2004
6:YongJun Gu et al. APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. 2003
7:Harald Steiner et al. PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrin. 2002


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