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ExactAntigen integrin beta 1 Antibody Review
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This is a review about integrin beta1 antibodies, based on 32 published articles using integrin beta1 antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited integrin beta1 antibody. Information in this review (with links to publications) can be searched freely.
list by method: blocking or activating expriments, ELISA, EMSA, flow cytometry, immunocytochemistry, immunohistochemistry, immunoprecipitation, western blot
SEROTEC    search SEROTEC ITGB1 products
In 2003, Charles Kumar Thodeti et al. used Serotec monoclonal activated beta 1 integrin (clone 12G10) antibody in immunocytochemistry to study beta 1 integrin-dependent cell spreading and in 2005, Faye Hui Chen et al. used Serotec monoclonal integrin beta1 subunit (clone JBS5) antibody in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5).
SIGMA    search SIGMA ITGB1 products
Other Brands or Spellings: SIGMA-ALDRICH, SIGMA CHEMICAL, SIGMA CHEMICAL COMPANY, SIGMA-ALDRICH FINE CHEMICALS
In 2003, Maria J Calzada et al. used Sigma integrin alpha 3 beta 1-blocking antibody P1B5 to study the binding of thrombospondin-1 and thrombospondin-2 with alpha 6 beta 1 integrin.
CHEMICON
Other Brands or Spellings: UPSTATE BIOTECHNOLOGIES, UPSTATE, UPSTATE BIOTECHNOLOGY, CHEMICON INTERNATIONAL, UPSTATE CELL SIGNALING, UPSTATE CELL SIGNALING SOLUTIONS, UPSTATE BIOTECH, UPSTATE BIOTECHNOLOGY INC, UPSTATE LABORATORIES
Chemicon provides several monoclonal antibodies against integrin beta 1, applicable to either activate or block integrin beta 1 function, or to be used in ELISA, western blot, immunoprecipitation, immunocytochemistry, and immunohistochemistry. In 2001, C C Chen et al. used Chemicon monoclonal anti-integrin beta1 antibodies (JB1A, JBS5) in blocking experiments to study the induction of adhesive signaling in primary human skin fibroblasts. In 2002, Joseph M Schober used Chemicon anti-beta 1 (6S6) function-blocking monoclonal antibody to identify integrin alpha M beta 2 as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2). In 2004, Triantafyllos Chavakis et al. used the same 6S6 antibody to study the role of endothelial cell JAM-C. In 2005, Loredana Moro et al. used Chemicon beta1 integrin antibody P4G11 to activate integrin in order to study BRCA2 expression down-regulation induced by collagen type I. Ilaria Cascone et al. used anti-alpha5-beta1 (AB1950, clone JBS5) and anti-alpha2-beta1 (clone BHA2.1, JBS2) antibodies in western blot, immunoprecipitation, immunocytochemistry, and blocking experiment to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor. Faye Hui Chen et al. used Chemicon monoclonal antibody (clone B3B11) in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5), and Cristiane G Lin et al. used Chemicon function-blocking monoclonal integrin alpha 5 beta 1 antibody (JBS5) to study integrin-dependent NOV (CCN3) functions in wound healing.
In 2003, Janelle L Lauer-Fields et al. used Chemicon anti-beta 1 integrin monoclonal antibody in western blot, immunoprecipitation, and ELISA to study the interaction between melanoma cell CD44 with basement membrane collagen. In 2001 C C Chen et al. used Upstate Biotechnology monoclonal integrin beta1 (clone DE9)antibody in immunocytochemistry to study the induction of adhesive signaling in primary human skin fibroblasts. In 2004, Abha Sahni et al. used Chemicon alpha5beta1 integrin (JBS5) antibody and alphaVbeta1 integrin (JB1A and LM142) antibodies in western blot and immunoprecipitation to study endothelial cell proliferation stimulated by FGF-2. In 2005, Ju-Eun Oh et al. used Chemicon monoclonal anti-integrin beta-1 (P4C10) antibody in flow cytometry to study the beta-ig-h3-mediated keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha-3,beta-1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. In 2005, Patrick A Kiely et al. used Chemicon International anti-beta1 integrin polyclonal antibody in western blot and immunoprecipitation to study cells with mutant IGF-I receptor at tyrosines 1250 and 1251.
Upstate Biotechnology or Chemicon integrin beta1 antibodies have been used in western blot experiments. In 2003, Josiane Sancacau et al. used Upstate Biotechnology integrin beta1 (clone DE9, mIgG2b) antibody to study the migratory-adhesive switch in Ewing's Sarcoma Cells triggered by matrix metalloproteinase-9 silencing. In 2004, Chun Chen et al. used CHEMICON International polyclonal anti-integrin beta 1 antibody to study the interaction of spermidine/spermine N1-acetyltransferase with integrin 9 subunit cytoplasmic domain which enhances cell migration, and Diane R Bielenberg et al. used Chemicon anti human integrin beta 1 2251 monoclonal antibody and anti hman alpha 5 beta 1 1950 antibody to study semaphorin 3F-induced tumor phenotype. In 2005, Richard Seonghun Nho et al. used Chemicon monoclonal ITGB1 antibody to investigate the role of integrin-linked kinase in Akt phosphorylation and fibroblast survival, and Songmin Cai et al. used Chemicon rabbit polyclonal integrin beta 1 antibody to study the effect of CD98 on integrin beta 1 function in polarized epithelial cells.
INVITROGEN
Other Brands or Spellings: BIOSOURCE, BIOSOURCE INTERNATIONAL, ZYMED, ZYMED LABORATORIES, CALTAG, MOLECULAR PROBES, MEDGENIX DIAGNOSTICS, MEDGENIX, DYNAL ASA
In 2003, Shr-Jeng Leu et al. used Invitrogen monoclonal integrin beta1 (P4C10) antibody in blocking experiments to identify a novel integrin alpha-6-beta-1 binding site in the angiogenic inducer CCN1. In 200,5 Cristiane G Lin et al. used Invitrogen integrin beta 1 antibody (P4C10) in immunohistochemistry and blocking or activating expriments to study integrin-dependent NOV (CCN3) functions in wound healing, Faye Hui Chen et al. used clone P4C10 in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) to support chondrocyte attachment through interaction with integrins, and Laura Lynch et al. used clone P4C10 in immunoprecipitation and polyclonal beta1 integrin (against cytoplasmic domain) antibody in western blot to study cell adhesion mediated by alpha5beta1 integrins in motile carcinoma cells.
SANTA CRUZ BIOTECHNOLOGY
Other Brands or Spellings: SANTA CRUZ, SANTA CRUZ BIOTECH, SANTA CRUZ BIOTECHNOLOGY INC., SANTA CRUZ BIOTECHNOLOGY INC, SANTZ CRUZ, SANTA CRUZ BIOTECHNOLOGIES
In 2003, Charles Kumar Thodeti et al. used Santa Cruz Biotechnology polyclonal beta 1 integrin (M-106) antibody in immunocytochemistry to study beta 1 integrin-dependent cell spreading. In 2005, Atsuhiko Hikita et al. used Santa Cruz Biotechnology anti-integrin-beta mouse monoclonal antibody in western blot to identify an alternatively spliced variant of Ca2+-promoted ras inactivator as a possible regulator of RANKL shedding, and Karim Kaabeche et al. used it in western blot to study the functional link between FGFR2 signaling and Cbl-mediated alpha-5-integrin expression in osteoblasts.
COULTER IMMUNOTECH
Other Brands or Spellings: BECKMAN COULTER, IMMUNOTECH, IMMUNOTECH-COULTER, IMMUNOTECH INTERNATIONAL, COULTER-IMMUNOTECH
In 2003, Josiane Sancacau et al. used Coulter Immunotech monoclonal anti-beta-1 antibody in flow cytometry and blocking expriment to study the migratory-adhesive switch in Ewing's Sarcoma Cells triggered by matrix metalloproteinase-9 silencing, and in 2005, Faye Hui Chen et al. used Coulter Corporation monoclonal antibody (clone 4B4) in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5).
DAKO Other Brands or Spellings: DAKOCYTOMATION, DAKO CYTOMATION, DAKO DIAGNOSTIC, DAKO CORP, DAKO CORPORATION, DAKO CORP., DAKO DIAGNOSTICS, DAKO A/S, DAKO DIAGNOSTIKA, DAKO LABORATORIES, DAKO-CYTOMATION, DAKO A/F, DAKOPATTS
In 2004, Neil C Henderson et al. used Dako anti-human beta1 integrin antibody (K20) in immunoprecipitation to study the interaction of CD98hc (SLC3A2) with beta1 integrins.
ANCELL
In 2002, D J Bloor et al. used Ancell beta 1 integrin mouse monoclonal antibody in immunohistochemistry to study its expression during human preimplantation embryo development.
ATCC
Other Brands or Spellings: AMERICAN TYPE CULTURE COLLECTION
In 2003, Maria J Calzada et al. used American Type Culture Collection monoclonal integrin beta 1-activating antibody TS2/16 to study the binding of thrombospondin-1 and thrombospondin-2 with alpha6beta1 integrin, and in 2005 Richard Seonghun Nho et al. used ATCC HB-243 TS2/16 beta 1 integrin-activating antibody to investigate the role of integrin-linked kinase in Akt phosphorylation and fibroblast survival.
BECTON DICKINSON
Other Brands or Spellings: BD BIOSCIENCES, BD, BD BIOSCIENCES CLONTECH, BD BIOSCIENCES PHARMINGEN, BD TRANSDUCTION LABORATORIES, BD TRANSDUCTION LABORATORY, TRANSDUCTION LABORATORIES, PHARMINGEN, PHARMINOGEN, BD PHARMINGEN, TRANSDUCTION LABORATORY, BECTON DICKINSON TRANSDUCTION LABORATORIES, BD TRANSDUCTION
In 2002 Naoyuki Anzai et al. used Becton Dickinson anti-CD29 monoclonal antibody (clone 13) in western blot to study the association between c-kit and transmembrane 4 superfamily proteins. In 2005, Xiaoyu Zhu et al. used Pharmingen anti-human beta1 integrin antibody in western blot and immunoprecipitation to study the role of E1AF in the activation of the human GalT I gene in highly metastatic lung cancer cells, and Loredana Moro et al. used BD Transduction Laboratory monoclonal beta1 integrin antibody in western blot to study the effect of down-regulation of BRCA2 expression by collagen type I. In 2006, Sylvia Major et al. tested BD Transduction Integrin beta1 antibody in western blot in the Abminer project.
ABCAM PLC
2006 A Persson et al. tested Abcam plc ITGB1 antibody in immunohistochemistry in the HPA (CAB003434) project.
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
In 2003 Charles Kumar Thodeti et al. used Developmental Studies Hybridoma Bank monoclonal function blocking beta 1 integrin (AIIB2) antibody to study beta 1 integrin-dependent cell spreading.
ERIC RUBINSTEIN (INSERM U268, FRANCE)
In 2001 S Charrin et al. ip, used Eric Rubinstein (INSERM U268, France) monoclonal anti-beta 1 integrin antibody (beta 1-vjf) in western blot and immunoprecipitation to study CD9 and CD81 tetraspanin complexes.
EXBIO
In 2005, Konstantinos G Drosopoulos et al. used Exbio anti-CD29 (MEM101A) antibody in flow cytometry to study the biological function of TRAIL induced apoptosis in human colon cells.
NEOMARKERS
Other Brands or Spellings: LAB VISION, LABVISION, NEOMARKER, LAB VISION/NEOMARKERS
In 2002 Henri-Noel Fournier et al. used Neomarkers monoclonal antibody 4B7R directed against human beta1 integrin in immunocytochemistry to provide the first evidence that the tumor suppressor nm23-H2 could act on beta1 integrin-mediated cell adhesion by interacting with one of the integrin partners ICAP-1alpha.
NOVOCASTRA LABORATORIES
Other Brands or Spellings: NOVOCASTRA
In 2004, Ryoko Yamauchi et al. used Novocastra Laboratories monoclonal anti-human CD29 antibody in immunohistochemistry to study the upregulation of SR-PSOX/CXCL16 and recruitment of CD8+ T Cells in cardiac valves during inflammatory valvular heart disease.
Articles Reviewed
1. C C Chen et al. The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. 2001
2. S Charrin et al. The major CD9 and CD81 molecular partner. Identification and characterization of the complexes. 2001
3. D J Bloor et al. Expression of cell adhesion molecules during human preimplantation embryo development. 2002
4. Henri-Noël Fournier et al. Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement. 2002
5. Naoyuki Anzai et al. C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors. 2002
6. Joseph M Schober et al. Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions. 2002
7. Charles Kumar Thodeti et al. ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. 2003
8. Janelle L Lauer-Fields et al. Melanoma cell CD44 interaction with the alpha 1(IV)1263-1277 region from basement membrane collagen is modulated by ligand glycosylation. 2003
9. Shr-Jeng Leu et al. Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61). 2003
10. Josiane Sancéau et al. Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in Ewing's sarcoma cells. 2003
11. Maria J Calzada et al. Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin. 2003
12. Ryoko Yamauchi et al. Upregulation of SR-PSOX/CXCL16 and recruitment of CD8+ T cells in cardiac valves during inflammatory valvular heart disease. 2004
13. Abha Sahni et al. Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3. 2004
14. Chun Chen et al. Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration. 2004
15. Triantafyllos Chavakis et al. The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo. 2004
16. Neil C Henderson et al. CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation. 2004
17. Laura Lynch et al. Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells. 2005
18. Diane R Bielenberg et al. Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. 2004
19. Cristiane G Lin et al. Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing. 2005
20. Patrick A Kiely et al. RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251. 2005
21. Xiaoyu Zhu et al. Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. 2005
22. Songmin Cai et al. CD98 modulates integrin beta1 function in polarized epithelial cells. 2005
23. Karim Kaabeche et al. Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation. 2005
24. Konstantinos G Drosopoulos et al. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. 2005
25. Ju-Eun Oh et al. Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. 2005
26. Loredana Moro et al. Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. 2005
27. Richard Seonghun Nho et al. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. 2005
28. Faye Hui Chen et al. Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins. 2005
29. Ilaria Cascone et al. Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. 2005
30. Atsuhiko Hikita et al. Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding. 2005
31. Sylvia Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006
32. A Persson et al. A human protein atlas based on antibody proteomics. 2006


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