| ExactAntigen |
| antibody |
|
Over 350,000 antibody products against 35,000 genes including 13,000 human genes. If you are looking for antibodies against a specific gene, please type in gene name in the box above and hit the search button. In the resultant gene webpage, select 'antibody' link for the correct gene to go to the antibody webpage. ExactAntigen.com contains two databases of antibody information. One is an antibody product database, which currently includes products from more than 40 suppliers; another is a webpage index database built with ExactAntigen web robot crawling over 750 antibody-related websites. Millions of the crawled webpages are analyzed by our advanced bioinformatic algorithm, and its results are presented to ExactAntigen visitors when searched in the webpage index database. |
| antibody type |
| There are two major types of antibodies. Monoclonal antibody is a type of immunoglobuin proteins derived from descendent cells of a single immune cell and is against a specific epitope. Production of monoclonal antibody tends to be more expensive than the other major type, polyclonal antibody. In ExactAntigen product database, 13311 genes including 7352 human genes have monoclonal antibodies. read more on monoclonal antibody. Polyclonal antibody is generally produced by immunizing rabbits, goats, and other large animials, and are a collection of immunoglobulin proteins with different specificities against the immunogen. ExactAntigen product database contains polyclonal antibodies for 30434 genes including 12988 human genes. read more on polyclonal antibody. |
| antibody species |
| Both reactive species and host species are considered.
human antibody. The largest collection of antibodies are against human genes. This is not surprising, since the main effort of biomedical research is to investigate the causes of various diseases and to devise sophisticated methods to detect, prevent and cure them. In total, 7352 human genes have corresponding monoclonal antibodies and 12988 of them have corresponding polyclonal antibodies. Antibodies derived from human and being used in laboratory research are extremely rare, and therapeutical antibodies tend to be humanized. see more on human antibody. mouse antibody. Mouse is both the most common immunizing host species for monoclonal antibody (and an occasional host for polyclonal antibodies) and an excellent research model for many diseases, and many areas of basic research. In total, 2929 mouse genes have monoclonal antibodies and 7799 mouse genes have polyclonal antibodies. Among monoclonal antibodies derived from various species, mouse origin accounts for about 85%. see more on mouse antibody, or murine antibody. rabbit antibody. Rabbit is mainly a host species for generating polyclonal antibodies, and more recently for producing monoclonal antibodies. Rabbit monoclonal antibodies reportedly have very low background in immunohistochemical studies, and have been gaining popularities. About 60% polyclonal antibodies and 4% of monoclonal antibodies were originated from rabbits. see more on rabbit antibody. rat antibody. Rat is very similar to mouse, in that it is both an excellent host animal for monoclonal antibodies, and a research model. In total, 2075 rat genes have monoclonal antibodies, and 6466 genes have polyclonal antibodies. Ten percent of monoclona antibodies are made in rats. see more on rat antibody. goat antibody. Goat, similar to rabbit, is mainly a host species for generating polyclonal antibodies. Compared to rabbits, goats can produce much more polyclonal antibodies due to its large size. About 23% percent of polyclonal antibodies are from goat. see more on goat antibody. chicken antibody. Chicken is an interesting choice as an antibody host species. It is the only non-mammalian species among the commonly used animal species, and thus may be able to generate antibodies against human genes for which other mammalian host animals are not suited. The antibody (IgY) from chicken can be purified from the eggyolks. About 3% of the polyclonal antibodies are made from chicken. see more on chicken antibody. |
| phospho antibody |
| phospho antibody. Protein phosphorylation is one of the major means of cell signaling transduction and enzymatic activity regulation. The advent of anti phospho antibodies is one of significant events in signal transduction research. ExactAntigen product database contains phospho-specific antibodies against 675 genes. see more on phospho antibody. |
| antibody conjugation |
| The direct conjugation of antibodies with various moieties enables the antigen-antibody complex to be easily detected or visualized without a secondary antibody. In total, 1456 human genes have one or more fluorecent conjugates, enzyme conjugates, or biotin conjugation. see more on conjugated antibody, and fluorescent antibody. Two most common conjugation moieties are FITC and biotin. see more on FITC antibody, and biotin antibody. |
| antibody application |
| Antibodies are used in different applications such as western blot (western blot antibody), immunocytochemistry, immunohistochemistry, ELISA, flow cytometry, immunoprecipitation, chromatin immunoprecipitation, and protein array. A few antibodies have been shown to either activate or inhibit the bound antigen molecules or other physiological processes. see blocking antibody for more detail. The most common application is western blot. see more on western blot antibody. |
| antibody review |
| It has been reported that many antibodies are not suitable for particular applications, and to help ExactAntigen visitors identify the most suitable antibodies for their specific need, we have reviewed 30820 antibody applications for 6435 selected genes based on 5809 formal publications as of November 2008. Among the 6435 genes which have been reviewed for their antibody applications in publications, some of more commonly used ones are listed here: GAD antibody, actin antibody, GFP antibody, integrin antibody, tubulin antibody,insulin antibody, and NeuN antibody. Many suppliers are cited in publications and in ExactAntigen antibody review database. Some of them are listed here: Sigma antibody, Santa Cruz antibody, Dako antibody, Chemicon antibody, and Upstate antibody. |
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