| Articles Reviewed |
| 1: | Neil C Henderson et al. Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis. 2008 |
| 2: | Weibin Shi et al. Endofin acts as a Smad anchor for receptor activation in BMP signaling. 2007 |
| 3: | Yoshihide Asano et al. Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation. 2007 |
| 4: | Chinatsu Tanaka et al. Long-range action of Nodal requires interaction with GDF1. 2007 |
| 5: | Lanying Song et al. Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. 2007 |
| 6: | Azeddine Atfi et al. The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor. 2007 |
| 7: | Ruoyun Tan et al. Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation. 2006 |
| 8: | Jennifer P Habashi et al. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. 2006 |
| 9: | Hendrik Ungefroren et al. Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta. 2005 |
| 10: | Lei Xu et al. Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model. 2005 |
| 11: | Takayuki Furumatsu et al. Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment. 2005 |
| 12: | Xiao Liang Zhang et al. Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling. 2005 |
| 13: | Constance E Runyan et al. The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells. 2005 |
| 14: | Shuanhu Zhou et al. Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling. 2005 |
| 15: | Nichole Boyer Arnold et al. Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein. 2005 |
| 16: | Yoshihide Asano et al. Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts. 2004 |
| 17: | Hiroaki Seto et al. Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts. 2004 |
| 18: | Daniel Besser et al. Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3. 2004 |
| 19: | Michael B Major et al. Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta. 2004 |
| 20: | Gabriella Lakos et al. Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. 2004 |
| 21: | Annie Lacerte et al. Activin inhibits pituitary prolactin expression and cell growth through Smads, Pit-1 and menin. 2004 |
| 22: | Mario Schiffer et al. A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. 2004 |
| 23: | Lisa Choy et al. Transforming growth factor-beta inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. 2003 |
| 24: | Celine Prunier et al. The oncoprotein Ski acts as an antagonist of transforming growth factor-beta signaling by suppressing Smad2 phosphorylation. 2003 |
| 25: | Heather B Adkins et al. Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo. 2003 |
| 26: | Tetsuro Watabe et al. TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. 2003 |
| 27: | Biao Hu et al. Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression. 2003 |
| 28: | Dirk Haller et al. Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation. 2003 |
| 29: | Katrien Janssens et al. Transforming growth factor-beta 1 mutations in Camurati-Engelmann disease lead to increased signaling by altering either activation or secretion of the mutant protein. 2003 |
| 30: | Pedro Soto et al. SMAD2 and SMAD7 involvement in the post-translational regulation of Muc4 via the transforming growth factor-beta and interferon-gamma pathways in rat mammary epithelial cells. 2003 |
| 31: | Marina Macias-Silva et al. Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration. 2002 |
| 32: | Ya Chung Tian et al. Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly. 2002 |
| 33: | Chunming Dong et al. Deficient Smad7 expression: a putative molecular defect in scleroderma. 2002 |
| 34: | Susan Fanayan et al. Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling. 2002 |
| 35: | Wen-Bin Chen et al. Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells. 2002 |
| 36: | Wen Xie et al. Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. 2002 |
| 37: | Lilly Y W Bourguignon et al. Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells. 2002 |
| 38: | Zhongfa Yan et al. Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1. 2002 |
| 39: | M Furuhashi et al. Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway. 2001 |
| 40: | H Watanabe et al. Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells. 2001 |