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MDM2 antibody review
MDM2 antibodies
This is a review about MDM2 antibodies, based on 20 published articles using MDM2 antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited MDM2 antibody. Information in this review (with links to publications) can be searched freely.
EMSA (emsa), immunocytochemistry (ic), immunohistochemistry (ih), immunoprecipitation (ip), western blot (wb)
SANTA CRUZ BIOTECHNOLOGY    search Santa Cruz Biotechnology MDM2 products
includes other brands or spellings
emsa    Santa Cruz anti-mdm2 antibody K-20 (SC-1022) was used in human HeLa cells and in EMSA to study the role of CDIR for apoptosis.
ic, ip, wb    Santa Cruz Biotechnology antibody specific to Mdm2 (clone SMP14) was used in western blot, immunoprecipitation and immunocytochemistry to study the role of Mdm2 to bind to Nbs1 at sites of DNA damage and regulate double strand break repair.
ip, wb    Santa Cruz Biotech Hdm2 (Smp-14 and N-20) antibodies were used in western blot and immunoprecipitation to study regulation of p53 by Yin Yang 1.
ip    Santa Cruz polyclonal anti-MDM2 was used in immunoprecipitation to isolate MDM2 from human SJSA cells.
ip    SCBT MDM2 (D-12) antibody was used in immunoprecipitation to investigate the regulation of ER alpha proteolysis and transcription.
wb    Santa Cruz Biotechnology anti-Mdm2 antibody was used in western blot to study the function of Frag1 protein in higher eukaryotes.
wb    Santa Cruz MDM2 (SMp14) antibody was used in western blot to study p53 protein levels and activity regulation.
wb    Santa Cruz Biotechnology mouse anti-Mdm2 monoclonal antibody was used in western blot to detect Mdm2 levels in human MCF7 cells.
wb    Santa Cruz Biotechnology murine monoclonal anti-MDM2 antibody was used in western blot to study expression of p53, ErbB1, ErbB2, and Raf-1 in lung cancer.
wb    SCBT MDM2 antibody was used in western blot to study the effect of Gadd45a on Bim.
wb    Santa Cruz Biotechnology Inc MDM2 antibody was used in western blot to study the effect of human p53 serine 46 phosphorylation on promoter selection and apoptosis.
EMD BIOSCIENCES    search EMD Biosciences MDM2 products
includes other brands or spellings
ih    Calbiochem mouse monoclonal anti-MDM2 that recognizes the carboxy-terminal portion of the MDM2 protein was used in immunohistochemistry to study translocation, deletion/amplification, and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma.
ip, wb    Calbiochem mouse MDM2 monoclonal antibody was used in western blot and immunoprecipitation to study the role of beta-arrestin in ubiquitination and down-regulation of the insulin-like growth factor-1 receptor.
wb    Oncogene Research Products MDM2 (Ab-2) antibody was used in western blot to study p53 protein levels and activity regulation.
wb    Oncogene anti-MDM2 (clone Ab-1 and clone Ab-3) antibodies were used in western blot to identify MDM2 as a mediator of DNA damage-induced MDMX degradation.
wb    Calbiochem monoclonal anti-human MDM2 antibody Ab-1 was used in western blot to study the effect of p73β on p57KIP2 expression.
wb    Oncogene MDM2 antibody was used in western blot to study the effect of Epstein-Barr virus lytic replication on ATM checkpoint signal transduction.
THERMO FISHER SCIENTIFIC    search Thermo Fisher Scientific MDM2 products
includes other brands or spellings
wb    Lab Vision MDM2 (Ab-1) antibody was tested in western blot by Abminer.
A J LEVINE (DEPARTMENT OF MOLECULAR BIOLOGY, PRINCETON UNIVERSITY, PRINCETON,
wb    A. J. Levine (Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA) anti-MDM2 monoclonal antibody was used in western blot to study the effect of MDM4 (MDMX) overexpression on apoptosis.
CN BIOSCIENCES
ih    CN Biosciences mouse monoclonal anti-MDM2 that recognizes amino acid residues 26–169 of the human MDM2 protein and clone 1B10 was used in immunohistochemistry to study translocation, deletion/amplification, and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma.
DIANOVA
ih    Dianova anti-mdm2 (clone IF-2) monoclonal antibody was used in immunohistochemistry to study its expression in paired initial and recurrent glioblastoma multiforme.
SANTA CRUTZ
ic, ip    Santa Crutz mouse anti-Mdm2 antibody SMP14 was used in immunoprecipitation and immunocytochemisty to study the effect of 14-3-3σ on p53 and tumor growth.


Articles Reviewed
1. Eva Röijer et al. Translocation, deletion/amplification, and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma. 2002
2. Eva Blint et al. Induction of p57(KIP2) expression by p73beta. 2002
3. Xiaodan Yu et al. Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228. 2002
4. Ksenya Shchors et al. Cell death inhibiting RNA (CDIR) derived from a 3'-untranslated region binds AUF1 and heat shock protein 27. 2002
5. Daniel J Freeman et al. PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. 2003
6. A M Stark et al. p53, mdm2, EGFR, and msh2 expression in paired initial and recurrent glioblastoma multiforme. 2003
7. Hidehiko Kawai et al. DNA damage-induced MDMX degradation is mediated by MDM2. 2003
8. Heng-Yin Yang et al. 14-3-3 sigma positively regulates p53 and suppresses tumor growth. 2003
9. Francesca Mancini et al. MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis. 2004
10. Guangchao Sui et al. Yin Yang 1 is a negative regulator of p53. 2004
11. Mu-Shui Dai et al. Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5. 2004
12. Ayumi Kudoh et al. Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment. 2005
13. Jodi R Alt et al. Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair. 2005
14. Lindsey D Mayo et al. Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified. 2005
15. Leonard Girnita et al. {beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. 2005
16. Tong Tong et al. Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria. 2005
17. Christopher C Valley et al. Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus. 2005
18. Hideshi Ishii et al. Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis. 2005
19. Wensheng Yan et al. GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner. 2006
20. Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006


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