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LCK antibody review
LCK antibodies
This is a review about LCK antibodies, based on 16 published articles using LCK antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited LCK antibody. Information in this review (with links to publications) can be searched freely.
immunocytochemistry (ic), immunohistochemistry (ih), immunoprecipitation (ip), western blot (wb)
CELL SIGNALING TECHNOLOGY    search Cell Signaling Technology LCK products
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wb    Cell Signaling Technology rabbit anti-phospho-Lck (Y394) antibody was used in western blot to study the mechanism for regulating the initiation of TCR signal transduction in human peripheral blood T lymphoblasts.
wb    Cell Signaling Technology antibodies specific for the phosphorylated Tyr505 of Lck (p505Lck) were used in western blot to demonstrates that LAT negatively regulates Lck activity in lipid rafts and preferentially co-immunoprecipitates with the ‘open’-active form of the kinase in these domains.
EPITOMICS    search Epitomics LCK products
ih    Epitomics LCK antibody was tested in immunohistochemistry by HPA (CAB003816) .
SANTA CRUZ BIOTECHNOLOGY    search Santa Cruz Biotechnology LCK products
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ic, ih, ip, wb    Santa Cruz Biotechnology rabbit polyclonal anti-Lck antibody and mouse monoclonal anti-Lck antibody, which were used in human MCF-7 cells and paraffin sections from human tumor, and which were respectively used in immunoprecipitation, immunocytochemistry and immunohistochemistry, western blot, to study the role for the effect of hypoxia on cross-talk between Syk and Lck in breast cancer progression and angiogenesis.
ip, wb    Santa Cruz Biotechnology mouse monoclonal anti-Lck mAb (clone 3A5) was used in western blot and immunoprecipitation to study the Initiation of CD38 signaling in T Cells within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor.
ip, wb    Santa Cruz Biotechnology monoclonal anti-Lck antibody (clone 3A5) and polyclonal antibody to Lck was used in immunoprecipitation and western blot to demonstrates that LAT negatively regulates Lck activity in lipid rafts and preferentially co-immunoprecipitates with the ‘open’-active form of the kinase in these domains.
wb    Santa Cruz Biotechnology anti-Lck antibody was used in western blot to study positive and negative signaling by the natural killer cell receptor 2B4 (CD244).
wb    Santa Cruz rabbit polyclonal anti-lck antibody was used in western blot to study tumor necrosis factor-alpha -induced intercellular adhesion molecule-1 expression.
wb    Santa Cruz Biotechnology anti-Lck antibody was used in western blot to study that membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.
wb    SCBT lck (3A5) antibody was used in western blot to study the lck degradation and refractory state in CD8+ cytotoxic T lymphocytes.
BD BIOSCIENCES    search BD Biosciences LCK products
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ip    BD PharMingen rabbit p56lck Ab was used in immunoprecipitation to study a potential role for tyrosine phosphatases.
wb    BD Transduction lck antibody was tested in western blot by Abminer.
wb    BD Biosciences anti-Lck monoclonal antibody was used in western blot to study a 10-aa-long sequence in SLP-76 upstream of the Gads binding site which is essential for T cell development and function.
wb    BD Transduction Laboratories anti-Lck antibody was used in western blot to study early T cell signaling events in PUFA-enriched T cells.
wb    BD polyclonal rabbit anti-lck antibody was used in western blot to study the lck degradation and refractory state in CD8+ cytotoxic T lymphocytes.
MILLIPORE    search Millipore LCK products
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ih, wb    Upstate Biotechnology rabbit anti-Lck antibody was used in western blot and 3A5 mouse anti-Lck mAb used in immunohistochemistry to study the mechanism for regulating the initiation of TCR signal transduction in human peripheral blood T lymphoblasts.
wb    Upstate Biotechnology monoclonal anti-tyrosine kinase Lck antibody was used in frozen lens capsule-epithelium samples from porcine eyes and in western blot to study the effect of SRC-family tyrosine kinases on Na, K-ATPase activity in lens epithelium.
INVITROGEN    search Invitrogen LCK products
includes other brands or spellings
ip, wb    Biosource anti-phospho-Lck (Ser-158) and anti-total-Lck antibodies were used to investigate the activation of Erk1/2 by intracellular M. leprae.
THERMO FISHER SCIENTIFIC    search Thermo Fisher Scientific LCK products
includes other brands or spellings
wb    NeoMarkers anti-Lck antibody was used in western blot to detect Lck in the pull-downs from Jurkat cell lysates by GST-ADAM cytoplasmic domain proteins.


Articles Reviewed
1. Zaruhi Poghosyan et al. Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases. 2002
2. Andrew E Schade et al. Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction. 2002
3. Christine Guntermann et al. CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases. 2002
4. Maximilian Zeyda et al. LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids. 2002
5. Panagiotis S Kabouridis et al. Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells. 2003
6. Wei-Chien Huang et al. c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression. 2003
7. Pilar Muñoz et al. CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor. 2003
8. Larry D Bozulic et al. The influence of SRC-family tyrosine kinases on Na,K-ATPase activity in lens epithelium. 2005
9. Céline Charvet et al. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76. 2005
10. Philipp Eissmann et al. Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244). 2005
11. Michael Uhlin et al. Regulation of lck degradation and refractory state in CD8+ cytotoxic T lymphocytes. 2005
12. Nikos Tapinos et al. Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli. 2005
13. Lalit Kumar et al. A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function. 2005
14. Goutam Chakraborty et al. Hypoxia regulates cross-talk between Syk and Lck leading to breast cancer progression and angiogenesis. 2006
15. Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006
16. Anja Persson et al. A human protein atlas based on antibody proteomics. 2006


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