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LAT antibody review
LAT antibodies
This is a review about LAT antibodies, based on 9 published articles using LAT antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited LAT antibody. Information in this review (with links to publications) can be searched freely.
immunohistochemistry (ih), immunoprecipitation (ip), western blot (wb)
CELL SIGNALING TECHNOLOGY    search Cell Signaling Technology LAT products
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wb    Cell Signaling Technology anti-phospho-LAT antibody was used in western blot to detect phospho-LAT in ZAP-70-deficient Jurkat T cell line P116 transfected with ZAP-70.
wb    Cell Signaling Technology anti-LAT and anti-phospho-LAT antibodies were used in western blot to study the role of the innate immune signaling molecule IRAK-4 in T cell activation.
BD BIOSCIENCES    search BD Biosciences LAT products
includes other brands or spellings
wb    BD Transduction LAT antibody was tested in western blot by Abminer.
MILLIPORE    search Millipore LAT products
includes other brands or spellings
ih, ip    Upstate Biotechnology rabbit anti-LAT antibody was used in immunoprecipitation and immunohistochemistry to study the mechanism for regulating the initiation of TCR signal transduction in human peripheral blood T lymphoblasts.
ip, wb    Upstate Biotechnology polyclonal anti-LAT antibody was used in human Jurkat cells and in immunoprecipitation, western blot to study the kinetic changes in LAT accumulated in aggregated rafts.
ip, wb    Upstate Biotechnology anti-LAT antibody was used in western blot and immunoprecipitation to demonstrates that LAT negatively regulates Lck activity in lipid rafts and preferentially co-immunoprecipitates with the ‘open’-active form of the kinase in these domains.
wb    Upstate Biotechnology polyclonal antibody anti-LAT was used in western blot to study the Initiation of CD38 signaling in T Cells within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor.
wb    Upstate Biotechnologies rabbit anti-LAT monoclonal antibody was used in western blot to study that membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.
wb    Upstate Biotechnology anti-LAT polyclonal antibody was used in western blot to detect LAT in ZAP-70-deficient Jurkat T cell line P116 transfected with ZAP-70.
wb    Upstate Biotechnology anti-LAT antibody was used in western blot to study early T cell signaling events in PUFA-enriched T cells.


Articles Reviewed
1. Andrew E Schade et al. Lipid raft heterogeneity in human peripheral blood T lymphoblasts: a mechanism for regulating the initiation of TCR signal transduction. 2002
2. Maximilian Zeyda et al. LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids. 2002
3. Natsuko Tanimura et al. Dynamic changes in the mobility of LAT in aggregated lipid rafts upon T cell activation. 2003
4. Panagiotis S Kabouridis et al. Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells. 2003
5. Pilar Muñoz et al. CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor. 2003
6. Seiji Goda et al. Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein. 2004
7. Céline Charvet et al. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76. 2005
8. Nobutaka Suzuki et al. A critical role for the innate immune signaling molecule IRAK-4 in T cell activation. 2006
9. Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006


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