ABDSEROTEC search AbDSerotec ITGB3 products
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| wb | | Serotec anti-integrin beta 3 antibody was used in western blot to detect integrin subunits from patient and control platelets and T cells. |
SIGMA-ALDRICH search Sigma-Aldrich ITGB3 products
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| block | | Sigma anti-alpha5beta3 integrin functional blocking antibodies (product LM609) was used in blocking experiments to study the role of connective tissue growth factor in lung adenocarcinoma invasion and metastasis. |
SANTA CRUZ BIOTECHNOLOGY search Santa Cruz Biotechnology ITGB3 products
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| wb | | Santa Cruz Biotechnology anti-beta3 antibody (SC-6627) was used in western blot to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor. |
BD BIOSCIENCES search BD Biosciences ITGB3 products
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| flow | | Becton Dickinson phycoerythrin (PE) –conjugated anti-CD61 antibody (VI-PL2) was used in human MGS cells and in flow cytometry to study the association between mutations of GATA-1 gene and transient myeloproliferative disorder of Down syndrome. |
MILLIPORE search Millipore ITGB3 products
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| block, ip | | CHEMICON International anti-alphaV-beta3 (25E11, clone LM609) antibodies were used in immunoprecipitation and blocking experiment to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor. |
| block | | Chemicon antibody against beta3 integrin was used in blocking experiment to study the role of p42/44 MAPK and protein kinase B in CTGF induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. |
| block | | Chemicon monoclonal integrin alpha-v-beta-3 (LM609) antibody was used in blocking experiments to identify a novel integrin alpha-6-beta-1 binding site in the angiogenic inducer CCN1. |
| block | | Chemicon function-blocking monoclonal integrin alpha v beta 3 antibody (LM609) was used in blocking or activating expriments to study integrin-dependent NOV (CCN3) functions in wound healing. |
| block | | Chemicon anti-integrin beta3 polyclonal antibody was used in blocking expriments to study the regulation of cap-dependent translation by fibronectin. |
| ih | | Chemicon polyclonal rabbit antihuman integrin beta3 was used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
| ip, wb | | Chemicon alphaVbeta3 integrin antibody (LM609) was used in to study endothelial cell proliferation stimulated by FGF-2. |
| wb | | Chemicon polyclonal anti-integrin beta 3 antibody and anti-integrin alphavbeta3 antibody LM609 were used in human cells and in western blot to study the role for tethering-induced signaling mode for alpha5beta1 integrin in phosphorylation of FAK Y397. |
INVITROGEN search Invitrogen ITGB3 products
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| wb | | BioSource International anti-phospho integrin beta 3 pY773 (Y747 in mice) antibody was used in western blot to study the effect of Eph kinases and ephrins on thrombus growth and stability in platelets. |
ATCC search ATCC ITGB3 products
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| block | | ATCC monoclonal anti-integrins-β3 antibody 7E3 was used in human HEK-293 cells (which was transfected uPAR cDNA) and in blocking expriments to study the role of sequences within domain II of the urokinase receptor for differential ligand recognition. |
BARRY COLLER (ROCKEFELLER UNIVERSITY)
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| ih | | Barry Coller (Rockefeller University) mouse monoclonal GPIIb/IIIa complex antibody (10E5) was used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
NOVOCASTRA
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| ih | | Novocastra ITGB3 antibody was tested in immunohistochemistry by HPA (CAB002501) . |
THOMAS KUNICKI (SCRIPPS RESEARCH INSTITUTE)
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| ih | | Thomas Kunicki (Scripps Research Institute) mouse monoclonal GPIIb/IIIa complex antibody (AP2) and mouse monoclonal GPIIIa antibody (AP3) were used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
Articles Reviewed |
| 1. John K G Crean et al. The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. 2002 |
| 2. Alison McDowall et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. 2003 |
| 3. Nurit Rosenberg et al. Major mutations in calf-1 and calf-2 domains of glycoprotein IIb in patients with Glanzmann thrombasthenia enable GPIIb/IIIa complex formation, but impair its transport from the endoplasmic reticulum to the Golgi apparatus. 2003 |
| 4. Yang Li et al. Sequences within domain II of the urokinase receptor critical for differential ligand recognition. 2003 |
| 5. Gang Xu et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. 2003 |
| 6. Shr-Jeng Leu et al. Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61). 2003 |
| 7. Qi Shi et al. A novel mode for integrin-mediated signaling: tethering is required for phosphorylation of FAK Y397. 2003 |
| 8. Cheng-Chi Chang et al. Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis. 2004 |
| 9. Abha Sahni et al. Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3. 2004 |
| 10. Cristiane G Lin et al. Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing. 2005 |
| 11. Chiara Gorrini et al. Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways. 2005 |
| 12. Nicolas Prévost et al. Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. 2005 |
| 13. Ilaria Cascone et al. Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. 2005 |
| 14. Anja Persson et al. A human protein atlas based on antibody proteomics. 2006 |