BIOLEGEND search BioLegend ITGB2 products
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| block | | BioLegend monoclonal anti-integrin subunits beta 2 antibody was used in human THP-1 cells and in blocking exprements to study the role for tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) in the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1). |
ABDSEROTEC search AbDSerotec ITGB2 products
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| flow | | Serotec monoclonal integrin beta 2 MEM148 antibody (recognizing the hybrid domain) was used in flow cytometry to study the function of beta2 I Domain of Integrin alphaMbeta2. |
SANTA CRUZ BIOTECHNOLOGY search Santa Cruz Biotechnology ITGB2 products
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| ih | | Santa Cruz Biotechnology mouse anti-human integrin beta 2 (CD18) monoclonal antibody (P4H9) was used in immunohistochemistry to study PR3 induction in human oral epithelial cells. |
BD BIOSCIENCES search BD Biosciences ITGB2 products
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| flow | | Pharmingen monoclonal integrin beta 2 6.7 antibody was used in flow cytometry to study the function of beta2 I Domain of Integrin alphaMbeta2. |
| flow | | Pharmingen murine activating anti-CD18 antibody (clone M18/2) was used in flow cytometry to study the role of oxidants and Lyn in SHIP regulation. |
| ih | | BD Biosciences anti-FITC-labeled MI/70 Mac-1 antibody was used in cryosections from mouse tumors and in immunohistochemistry to study the effect of tumor on sentinel lymph node lymphangiogenesis and lymph flow precede melanoma metastasis. |
MILLIPORE search Millipore ITGB2 products
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| block | | Chemicon anti-beta 2 (YFC118.3) function-blocking monoclonal antibody was used in blocking experiments to identify integrin alpha M beta 2 as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2). |
INVITROGEN search Invitrogen ITGB2 products
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| wb | | Caltag anti-Mac-1 antibody was used in western blot to study interaction of ATF2 with the coactivator ASC-2. |
ATCC search ATCC ITGB2 products
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| flow | | ATCC monoclonal antibody IB4 (recognizing Pro192–Glu197 of the beta 2I domain) was used in flow cytometry to study the function of beta2 I Domain of Integrin alphaMbeta2. |
BECKMAN COULTER search Beckman Coulter ITGB2 products
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| flow | | Beckman-Coulter mouse anti-CD18 mAb (clone 195N, IgG1) was used in flow cytometry to immply the possible function of Siglec-8 cross-linking to induce human eosinophil apoptosis. |
BIODESIGN
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| block | | Biodesign activating beta2-specific monoclonal antiobdy (MEM48) was used in blocking or activating expriments to study the function of beta2 I Domain of Integrin alphaMbeta2. |
M ROBINSON (SLOUGH BERKSHIRE, UK)
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| block | | M. Robinson (Slough Berkshire, UK) monoclonal beta2-integrin stimulating antibody Kim185 was used in blocking or activating expriments to study platelet-leukocyte interaction regulation. |
CARL G GAHMBERG (UNIVERSITY OF HELSINKI, FIN-00014 HELSINKI, FINLAND)
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| block, flow, ip, wb | | Carl G. Gahmberg (University of Helsinki, FIN-00014 Helsinki, Finland) integrin beta 2 antibody R7E4 (blocking antibody) was used in immunoprecipitation, flow cytometry, and blocking or activating expriments, and R2E7B antibody was used in western blot to study the regulation of LFA-1 activation. |
MA ARNAOUT (MASSACHUSETTS GENERAL HOSPITAL, BOSTON, MA)
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| ip | | M.A. Arnaout (Massachusetts General Hospital, Boston, MA) integrin beta 2 IB4 antibody (specific to heterodimeric LFA-1) was used in immunoprecipitation to study the regulation of LFA-1 activation. |
CANCER RESEARCH UK
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| wb | | Cancer Research UK anti-integrin beta 2 antibody was used in western blot to detect integrin subunits from patient and control platelets and T cells. |
Articles Reviewed |
| 1. Shyra Gardai et al. Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils. 2002 |
| 2. Joseph M Schober et al. Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions. 2002 |
| 3. Alison McDowall et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. 2003 |
| 4. Esra Nutku et al. Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis. 2003 |
| 5. Triantafyllos Chavakis et al. High molecular weight kininogen regulates platelet-leukocyte interactions by bridging Mac-1 and glycoprotein Ib. 2003 |
| 6. SunHwa Hong et al. Activation and interaction of ATF2 with the coactivator ASC-2 are responsive for granulocytic differentiation by retinoic acid. 2004 |
| 7. Akiko Uehara et al. Proinflammatory cytokines induce proteinase 3 as membrane-bound and secretory forms in human oral epithelial cells and antibodies to proteinase 3 activate the cells through protease-activated receptor-2. 2004 |
| 8. Driss Ehirchiou et al. Dual function for a unique site within the beta2I domain of integrin alphaMbeta2. 2005 |
| 9. Susanna C Fagerholm et al. Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms. 2005 |
| 10. Nina L Tsakadze et al. Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1). 2006 |
| 11. Maria I Harrell et al. Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. 2007 |