ABDSEROTEC search AbDSerotec ITGB1 products
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| block | | Serotec Ltd. monoclonal antibody against the integrin beta1 subunit (clone JBS5) was used in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) to support chondrocyte attachment through interaction with integrins. |
| ic | | Serotec monoclonal activated beta 1 integrin (clone 12G10) antibody was used in immunocytochemistry to study beta 1 integrin-dependent cell spreading. |
SIGMA-ALDRICH search Sigma-Aldrich ITGB1 products
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| block | | Sigma integrin alpha 3 beta 1-blocking antibody P1B5 was used in blocking or activating expriments to study the binding of thrombospondin-1 and thrombospondin-2 with alpha6beta1 integrin. |
SANTA CRUZ BIOTECHNOLOGY search Santa Cruz Biotechnology ITGB1 products
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| ic, ip, wb | | Santa Cruz Biotechnology mouse monoclonal anti-beta1-integrin antibody was used in immunocytochemistry, western blot an immunoprecipitation to study that neuregulin-1 enhances motility and migration of human astrocytic glioma cells. |
| ic | | Santa Cruz Biotechnology polyclonal beta 1 integrin (M-106) antibody was used in immunocytochemistry to study beta 1 integrin-dependent cell spreading. |
| ip, wb | | Santa Cruz Biotechnology polyclonal anti-integrin beta1 antibody (beta1-cyto) was used in human Jurkat cells and in immunoprecipitation, western blot to study the association of RanBPM with the plasma membrane and the interaction with the integrin LFA-1. |
| wb | | Santa Cruz Biotechnology anti-integrin-beta mouse monoclonal antibody was used in western blot to identify an alternatively spliced variant of Ca2+-promoted ras inactivator as a possible regulator of RANKL shedding. |
| wb | | Santa Cruz mouse anti-ß1 integrin antibody was used in western blot to study the functional link between FGFR2 signaling and Cbl-mediated alpha-5-integrin expression resulting in altered cell attachment and apoptosis in osteoblasts. |
DEVELOPMENTAL STUDIES HYBRIDOMA BANK search Developmental Studies Hybridoma Bank ITGB1 products
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| block | | Developmental Studies Hybridoma Bank monoclonal function blocking beta 1 integrin (AIIB2) antibody was used in blocking or activating expriments to study beta 1 integrin-dependent cell spreading. |
BD BIOSCIENCES search BD Biosciences ITGB1 products
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| flow | | BD Biosciences PharMingen anti-human CD29 antibody was used in human mesenchymal stem cells (hMSCs) and in flow cytometry to study the prolongation of life span of human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs). |
| ip, wb | | Pharmingen anti-human beta1 integrin antibody was used in western blot and immunoprecipitation to study the role of E1AF in the activation of the human GalT I gene in highly metastatic lung cancer cells. |
| wb | | BD Transduction Laboratory monoclonal beta1 integrin antibody was used in western blot to study the effect of down-regulation of BRCA2 expression by collagen type I. |
| wb | | BD Transduction Integrin beta1 antibody was tested in western blot by Abminer. |
| wb | | Becton Dickinson anti-CD29 monoclonal antibody (clone 13) was used in Western blot to study the association between c-kit and transmembrane 4 superfamily proteins. |
| wb | | Transduction Laboratories antibody to beta1 integrin was used in western blot to detect beta1 integrin in H69 human SCLC cells. |
| wb | | Transduction Laboratories anti-integrin beta1 antibody was used in human SH-EP cells and in western blot to study the effect of insulin-like growth factor I on mannitol-induced degradation of focal adhesion kinase and Akt. |
ABCAM search Abcam ITGB1 products
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| ih | | Abcam plc ITGB1 antibody was tested in immunohistochemistry by HPA (CAB003434) . |
MILLIPORE search Millipore ITGB1 products
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| block, ic, ip, wb | | CHEMICON International anti-alpha5-beta1 (AB1950, clone JBS5) and anti-alpha2-beta1 (clone BHA2.1, JBS2) antibodies were used in western blot, immunoprecipitation, immunocytochemistry and blocking experiment to study the regulation of the endothelial cell response to Ang-1 through stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor. |
| block | | Chemicon activating beta1 integrin antibody P4G11 was used to activate integrin to study the effect of down-regulation of BRCA2 expression by collagen type I. |
| block | | Chemicon monoclonal antibody against the integrin beta1 subunit (clone B3B11) was used in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) to support chondrocyte attachment through interaction with integrins. |
| block | | Chemicon anti-beta 1 (6S6) function-blocking monoclonal antibody was used in blocking experiments to identify integrin alpha M beta 2 as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2). |
| block | | Chemicon function-blocking monoclonal integrin alpha 5 beta 1 antibody (JBS5) was used in blocking or activating expriments to study integrin-dependent NOV (CCN3) functions in wound healing. |
| elisa, ip, wb | | Chemicon anti-beta 1 integrin monoclonal antibody was used in western blot, immunoprecipitation, and ELISA to study the interaction between melanoma cell CD44 with basement membrane collagen. |
| flow | | Chemicon monoclonal anti-integrin beta-1 (P4C10) antibody was used in flow cytometry to study the beta-ig-h3-mediated keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha-3, beta-1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. |
| ic | | Chemicon International monoclonal anti-integrin beta antibody was used in human bronchial epithelial 16HBE14o cells and in immunocytochemistry to study the interaction of human epithelial iNOS with EBP50 and the effect of which on polarized epithelial cell functions. |
| ip, wb | | Chemicon International anti-beta1 integrin polyclonal antibody was used in western blot and immunoprecipitation to study cells with mutant IGF-I receptor at tyrosines 1250 and 1251. |
| ip, wb | | Chemicon alpha5beta1 integrin (JBS5) antibody and alphaVbeta1 integrin (JB1A and LM142) antibodies were used in western blot and immunoprecipitation to study endothelial cell proliferation stimulated by FGF-2. |
| wb | | CHEMICON International polyclonal anti-integrin ß1 antibody was used in western blot to study the interaction of spermidine/spermine N1-acetyltransferase with integrin 9 subunit cytoplasmic domain which enhances cell migration. |
| wb | | Chemicon rabbit polyclonal integrin beta 1 antibody was used in western blot to study the effect of CD98 on integrin beta 1 function in polarized epithelial cells. |
| wb | | Chemicon International anti-integrin beta 1 antibody was used in western blot to detect integrin subunits from patient and control platelets and T cells. |
| wb | | Chemicon anti-human integrin beta1 monoclonal antibody was used in western blot to detect integrin beta1 in MA104 and Caco-2 cells. |
| wb | | Upstate Biotechnology integrin beta1 (clone DE9, mIgG2b) antibody was used in western blot to study the migratory-adhesive switch in Ewing's Sarcoma Cells triggered by matrix metalloproteinase-9 silencing. |
| wb | | Chemicon anti–human integrin beta 1 2251 monoclonal antibody and anti–human alpha 5 beta 1 1950 antibody were used in western blot to study Semaphorin 3F-induced tumor phenotype. |
| wb | | Chemicon monoclonal ITGB1 antibody was used in western blot to investigate the role of integrin-linked kinase in Akt phosphorylation and fibroblast survival. |
INVITROGEN search Invitrogen ITGB1 products
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| block, ih | | Invitrogen integrin beta 1 antibody (P4C10) was used in immunohistochemistry and blocking or activating expriments to study integrin-dependent NOV (CCN3) functions in wound healing. |
| block | | Invitrogen monoclonal antibody against the integrin beta1 subunit (clone P4C10) was used in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) to support chondrocyte attachment through interaction with integrins. |
| block | | Invitrogen monoclonal integrin beta1 (P4C10) antibody was used in blocking experiments to identify a novel integrin alpha-6-beta-1 binding site in the angiogenic inducer CCN1. |
| ip | | Invitrogen beta1 integrin monoclonal IgG1 (clone P4C10) was used in immunoprecipitation to study cell adhesion mediated by alpha5beta1 integrins in motile carcinoma cells. |
| wb | | BioSource International polyclonal beta1 integrin (against cytoplasmic domain) antibody was used in western blot to study cell adhesion mediated by alpha5beta1 integrins in motile carcinoma cells. |
ATCC search ATCC ITGB1 products
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| block | | American Type Culture Collection monoclonal anti-beta1 integrin antibody was used in blocking or activating experiments to study the effects of ZAP-70 mutations on beta1 integrin-induced increases in P116 Jurkat T cell adhesion to fibronectin. |
| block | | American Type Culture Collection monoclonal integrin beta 1-activating antibody TS2/16 was used in blocking or activating expriments to study the binding of thrombospondin-1 and thrombospondin-2 with alpha6beta1 integrin. |
| wb | | ATCC HB-243 TS2/16 {beta}1 integrin-activating antibody was used to investigate the role of integrin-linked kinase in Akt phosphorylation and fibroblast survival. |
ANCELL search Ancell ITGB1 products
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| ih | | Ancell beta 1 integrin mouse monoclonal antibody was used in immunohistochemistry to study its expression during human preimplantation embryo development. |
THERMO FISHER SCIENTIFIC search Thermo Fisher Scientific ITGB1 products
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| ic | | Neomarkers monoclonal antibody 4B7R directed against human beta1 integrin was used in immunocytochemistry to provide the first evidence that the tumor suppressor nm23-H2 could act on beta1 integrin-mediated cell adhesion by interacting with one of the integrin partners ICAP-1alpha. |
BECKMAN COULTER search Beckman Coulter ITGB1 products
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| block, flow | | Coulter Immunotech monoclonal anti-beta-1 antibody was used in flow cytometry and blocking expriment to study the migratory-adhesive switch in Ewing's Sarcoma Cells triggered by matrix metalloproteinase-9 silencing. |
| block | | Coulter Corporation monoclonal antibody against the integrin beta1 subunit (clone 4B4) was used in blocking experiments to study the function of cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) to support chondrocyte attachment through interaction with integrins. |
| flow | | Beckman Coulter anti-human CD29 antibody was used in human mesenchymal stem cells (hMSCs) and in flow cytometry to study the prolongation of life span of human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs). |
| flow | | Immunotech anti-human CD29 antibody was used in human mesenchymal stem cells (hMSCs) and in flow cytometry to study the prolongation of life span of human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs). |
| ic, ip | | DAKO FITC conjugated antibody against beta1 integrin (clone K20) was used in immunoprecipitation to isolate beta1 integrin from H69 human SCLC cells, and in immunocytochemistry to localize beta1 integrin in H69 SCLC cells. |
| ip | | Dako anti-human beta1 integrin antibody (K20) was used in immunoprecipitation to study the interaction of CD98hc (SLC3A2) with beta1 integrins required for transformation. |
LEICA MICROSYSTEMS search Leica Microsystems ITGB1 products
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| ih | | Novocastra Laboratories monoclonal anti-human CD29 antibody was used in immunohistochemistry to study the upregulation of SR-PSOX/CXCL16 and recruitment of CD8+ T Cells in cardiac valves during inflammatory valvular heart disease. |
CYTOTECH
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| flow | | Cytotech anti-human CD29 antibody was used in human mesenchymal stem cells (hMSCs) and in flow cytometry to study the prolongation of life span of human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs). |
EXBIO
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| flow | | Exbio anti-CD29 (MEM101A) antibody was used in flow cytometry to study the biological function of TRAIL induced apoptosis in human colon cells. |
Articles Reviewed |
| 1. D J Bloor et al. Expression of cell adhesion molecules during human preimplantation embryo development. 2002 |
| 2. Henri-Noël Fournier et al. Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement. 2002 |
| 3. Bhumsoo Kim et al. Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt. 2002 |
| 4. Naoyuki Anzai et al. C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors. 2002 |
| 5. Joseph M Schober et al. Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions. 2002 |
| 6. Paul A Glynne et al. Epithelial inducible nitric-oxide synthase is an apical EBP50-binding protein that directs vectorial nitric oxide output. 2002 |
| 7. Robert C Rintoul et al. Cross-linking CD98 promotes integrin-like signaling and anchorage-independent growth. 2002 |
| 8. Charles Kumar Thodeti et al. ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. 2003 |
| 9. Alison McDowall et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. 2003 |
| 10. Janelle L Lauer-Fields et al. Melanoma cell CD44 interaction with the alpha 1(IV)1263-1277 region from basement membrane collagen is modulated by ligand glycosylation. 2003 |
| 11. Patricia A Ritch et al. Neuregulin-1 enhances motility and migration of human astrocytic glioma cells. 2003 |
| 12. Shr-Jeng Leu et al. Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61). 2003 |
| 13. Josiane Sancéau et al. Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in Ewing's sarcoma cells. 2003 |
| 14. Maria J Calzada et al. Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin. 2003 |
| 15. Sarah L Londrigan et al. Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit. 2003 |
| 16. Ryoko Yamauchi et al. Upregulation of SR-PSOX/CXCL16 and recruitment of CD8+ T cells in cardiac valves during inflammatory valvular heart disease. 2004 |
| 17. Simona Denti et al. RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1. 2004 |
| 18. Seiji Goda et al. Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein. 2004 |
| 19. Abha Sahni et al. Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3. 2004 |
| 20. Chun Chen et al. Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration. 2004 |
| 21. Neil C Henderson et al. CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation. 2004 |
| 22. Laura Lynch et al. Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells. 2005 |
| 23. Diane R Bielenberg et al. Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. 2004 |
| 24. Cristiane G Lin et al. Integrin-dependent functions of the angiogenic inducer NOV (CCN3): implication in wound healing. 2005 |
| 25. Patrick A Kiely et al. RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251. 2005 |
| 26. Xiaoyu Zhu et al. Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. 2005 |
| 27. Masanori Terai et al. Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway. 2005 |
| 28. Songmin Cai et al. CD98 modulates integrin beta1 function in polarized epithelial cells. 2005 |
| 29. Karim Kaabeche et al. Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation. 2005 |
| 30. Konstantinos G Drosopoulos et al. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. 2005 |
| 31. Ju-Eun Oh et al. Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. 2005 |
| 32. Loredana Moro et al. Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. 2005 |
| 33. Richard Seonghun Nho et al. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. 2005 |
| 34. Faye Hui Chen et al. Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins. 2005 |
| 35. Ilaria Cascone et al. Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. 2005 |
| 36. Atsuhiko Hikita et al. Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding. 2005 |
| 37. Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006 |
| 38. Anja Persson et al. A human protein atlas based on antibody proteomics. 2006 |