BIOLEGEND search BioLegend ITGAL products
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| block | | BioLegend monoclonal anti-integrin subunits alpha L antibody was used in human THP-1 cells and in blocking exprements to study the role for tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) in the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1). |
SANTA CRUZ BIOTECHNOLOGY search Santa Cruz Biotechnology ITGAL products
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| ic, ip, wb | | Santa Cruz Biotechnology anti-LFA-1 antibodies (TS1.18 and TS1.22) were used in human Jurkat cells, and which were respectively used in immunoprecipitation, immunocytochemistry, western blot and western blot, immunoprecipitation, to study the association of RanBPM with the plasma membrane and the interaction with the integrin LFA-1. |
BD BIOSCIENCES search BD Biosciences ITGAL products
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| flow | | BD PharMingen monoclonal antibody against CD11a (clone G43-25B) was used in flow cytometry to study the important functional role of ICOS-ligand which is expressed on human endothelial cells to costimulate Th1 and Th2 cytokine secretion by memory CD4+ T cells. |
| wb | | BD Transduction Laboratories anti-integrin alphaL antibody (610826) was used in human Jurkat cells and in western blot to study the association of RanBPM with the plasma membrane and the interaction with the integrin LFA-1. |
INVITROGEN search Invitrogen ITGAL products
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| ic | | CALTAG Laboratories monoclonal anti-LFA-1 antibody MEM-25 was used in human Jurkat cells and in immunocytochemistry to study the kinetic changes in LAT accumulated in aggregated rafts. |
ATCC search ATCC ITGAL products
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| block, ic | | American Type Culture Collection anti-LFA-1 monoclonal antibodies TS1/22 and TS2/4 were used in immunocytochemistry and blocking or activating expriments to study the role of lymphocyte function-associated antigen-1 in cytotoxic T lymphocyte activity. |
| ic | | American Type Culture Collection anti-human LFA-1 (TS2/4) conjugated with AlexaFluor 546 was used in immunocytochemistry to detect LFA-1 in human PLC-gamma1-deficient Jurkat cells. |
V HOREJSI (INSTITUTE OF MOLECULAR GENETICS, PRAGUE, CZECH REPUBLIC)
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| block, wb | | V. Horejsi (Institute of Molecular Genetics, Prague, Czech Republic) integrin alpha L antibody (MEM-83) was used in western blot and activating expriments to study the regulation of LFA-1 activation. |
N HOGG (IMPERIAL CANCER RESEARCH FUND, LONDON, UK)
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| flow, ic | | N. Hogg (Imperial Cancer Research Fund, London, UK) integrin alpha L mAb24 antibody was used in immunocytochemistry and flow cytometry to study the regulation of LFA-1 activation. |
CANCER RESEARCH UK
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| wb | | Cancer Research UK anti-integrin alpha L antibody was used in western blot to detect integrin subunits from patient and control platelets and T cells. |
Articles Reviewed |
| 1. Saman Khayyamian et al. ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells. 2002 |
| 2. Alison McDowall et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. 2003 |
| 3. Natsuko Tanimura et al. Dynamic changes in the mobility of LAT in aggregated lipid rafts upon T cell activation. 2003 |
| 4. Koko Katagiri et al. Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1. 2004 |
| 5. Simona Denti et al. RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1. 2004 |
| 6. Nadia Anikeeva et al. Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes. 2005 |
| 7. Susanna C Fagerholm et al. Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms. 2005 |
| 8. Nina L Tsakadze et al. Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1). 2006 |