BD BIOSCIENCES search BD Biosciences ITGA2B products
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| flow | | Becton Dickinson phycoerythrin (PE) –conjugated anti-CD41a antibody (HIP8) was used in human MGS cells and in flow cytometry to study the association between mutations of GATA-1 gene and transient myeloproliferative disorder of Down syndrome. |
| flow | | Becton Dickinson fibrinogen receptor (PAC-1) monoclonal antibody (against only the activated form) was used in flow cytometry to study potassium channel role in P2Y12 receptor–mediated platelet functional responses. |
| flow | | Becton Dickinson anti-CD41 antibody was used in flow cytometry to study the effect of deficiet ribosomal protein S19 in CD34+ cells generated by siRNA to block erythroid development and mimic defects seen in Diamond-Blackfan anemia. |
MILLIPORE search Millipore ITGA2B products
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| ih | | Chemicon monoclonal GPIIb antibody CA3 was used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
BECKMAN COULTER search Beckman Coulter ITGA2B products
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| ih | | Immunotech mouse monoclonal GPIIb antibodies SZ22 (against the heavy chain) and P2 (recognizing GPIIb only when complexed with GPIIIa) were used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
| wb | | Immunotech anti-integrin alpha IIb antibody was used in western blot to detect integrin subunits from patient and control platelets and T cells. |
THOMAS KUNICKI (SCRIPPS RESEARCH INSTITUTE)
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| ih | | Thomas Kunicki (Scripps Research Institute) mouse monoclonal GPIIb/IIIa complex antibody (AP2) was used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
BARRY COLLER (ROCKEFELLER UNIVERSITY)
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| ih | | Barry Coller (Rockefeller University) mouse monoclonal GPIIb/IIIa complex antibody (10E5) was used in immunohistochemistry to study the effects of glycoprotein IIb mutations in patients with Glanzmann thrombasthenia. |
BECTON DICKINSON BIOSCIENCES
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| flow | | Becton Dickinson Biosciences anti-CD41 antibody was used in flow cytometry to study that notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1. |
Articles Reviewed |
| 1. Alison McDowall et al. A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. 2003 |
| 2. Nurit Rosenberg et al. Major mutations in calf-1 and calf-2 domains of glycoprotein IIb in patients with Glanzmann thrombasthenia enable GPIIb/IIIa complex formation, but impair its transport from the endoplasmic reticulum to the Golgi apparatus. 2003 |
| 3. Gang Xu et al. Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome. 2003 |
| 4. Haripriya Shankar et al. Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses. 2004 |
| 5. Eri Ishiko et al. Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1. 2005 |
| 6. Johan Flygare et al. Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia. 2005 |