ABDSEROTEC search AbDSerotec IGF1R products
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| ip | | Oxford Biomedical rabbit polyclonal IGFR-1 antibody was used in immunoprecipitation to study the effects of black tea polyphenols on IGF-I signal transduction pathways in normal prostate epithelial cells and Du145 prostate carcinoma cells. |
SANTA CRUZ BIOTECHNOLOGY search Santa Cruz Biotechnology IGF1R products
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| ic, ih | | Santa Cruz Biotechnology polyclonal anti-IGF1R ß subunit antibody was used in paraffin sections from patients (who had lower urinary tract symptoms and a benign prostate on digital rectal examination, TURP, metastatic prostate cancer) and human prostate cancer cell lines DU145 and PC3, which were respectively used in immunohistochemistry and immunocytochemistry, to study the role of the IGF1R in prostate cancer. |
| ip, wb | | Santa Cruz Biotechnology rabbit polyclonal anti-IGF-I {beta}-subunit receptor antibody was used in immunoprecipitation and western blot to study the expression level of insulin-like growth factor I receptors and insulin receptors in human micro- and macrovascular endothelial cells. |
| ip, wb | | Santa Cruz Biotechnology rabbit polyclonal anti-IGF1-R beta subunit antibody was used in human non-small cell lung cancer cell lines and in western blot, immunoprecipitation to study the mechanism of apoptosis inhibition by amphiregulin through an IGF1-dependent survival pathway in non-small cell lung cancer (NSCLC) cells. |
| ip, wb | | Santa Cruz Biotechnology polyclonal IGF-1R antibodies (N-20, C-20, and H-60) were used in western blot and immunoprecipitation to study the role of beta-arrestin in ubiquitination and down-regulation of the insulin-like growth factor-1 receptor. |
| ip | | Santa Cruz Biotechnology polyclonal anti-the beta subunit of IGF-I receptor (beta-IGFI-R) antibody (C-20) was used in human hepatoma (HepG2) calls and in immunoprecipitation to study the effect of the increasing of free, unbound insulin-like growth factor I on insulin responsiveness in human hepatoma G2 cells in culture. |
| ip | | Santa Cruz Biotechnology polyclonal anti-IGF-1R antibody was used in COS cells (which were ransfected with plasmids encoding HA-RACK1) and in immunoprecipitation to study the role for the interaction between RACK1 and insulin-like growth factor 1 (IGF-1) receptor in regulating IGF-1-mediated Akt activation and protection from cell death. |
| wb | | Santa Cruz Biotechnology polyclonal IGF-IR beta subunit C-20 antibody was used in western blot to study cell adhesion mediated by alpha5beta1 integrins in motile carcinoma cells. |
| wb | | Santa Cruz Biotechnology anti-IGF-IR α- and β-subunits antibody was used in mouse R cells (which was transfected with plasmids containing human cDNAs.) and in western blot to study the contributions of the different downstream pathways of IGF-IR to IGF-IR-mediated radioresistance. |
R & D SYSTEMS search R & D Systems IGF1R products
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| block | | R & D Systems monoclonal anti-human IGF-I receptor antibody (IGF-IR) was used in human Kaposi's sarcoma cells (KS cells) and in blocking expriments to study the molecular mechanisms through which HIV-1-Tat protein inhibits vincristine-induced apoptosis of KS cells. |
EMD BIOSCIENCES search EMD Biosciences IGF1R products
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| block | | Oncogene neutralizing human IGF-1 receptor antibody was used in blocking or activating expriments to study matrix metalloproteinase-13 expression in human chondrocytes. |
| elisa, ip | | Oncogene Research monoclonal antibody alpha IR-3 (which recognizes the IGF-IR alpha -subunit and only poorly recognizes the Hybrid-R) was used in ELISA and immunoprecipitation to study the biological characteristics of insulin/insulin-like growth factor I hybrid receptors. |
| ip, wb | | Calbiochem mouse monoclonal human IGF-1R antibody was used in western blot and immunoprecipitation to study the role of beta-arrestin in ubiquitination and down-regulation of the insulin-like growth factor-1 receptor. |
| ip | | Calbiochem IGF-IR mAb was used in immunoprecipitation to study cell adhesion mediated by alpha5beta1 integrins in motile carcinoma cells. |
MILLIPORE search Millipore IGF1R products
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| wb | | Upstate Biotechnology chicken polyclonal antibody that recognizes the IGF-IR alpha subunit was used in western blot to study the biological characteristics of insulin/insulin-like growth factor I hybrid receptors. |
IMMUNOGEN
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| wb | | ImmunoGen monoclonal anti-IGF-1R antibody ND122 was used in COS cells (which were ransfected with plasmids encoding HA-RACK1) and in western blot to study the role for the interaction between RACK1 and insulin-like growth factor 1 (IGF-1) receptor in regulating IGF-1-mediated Akt activation and protection from cell death. |
Articles Reviewed |
| 1. Russell D Klein et al. Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. 2002 |
| 2. Keiji Sakai et al. Increases in free, unbound insulin-like growth factor I enhance insulin responsiveness in human hepatoma G2 cells in culture. 2002 |
| 3. Patrick A Kiely et al. RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death. 2002 |
| 4. Maria Chiara Deregibus et al. HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells. 2002 |
| 5. Giles O Hellawell et al. Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease. 2002 |
| 6. Giuseppe Pandini et al. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. 2002 |
| 7. Amandine Hurbin et al. Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines. 2002 |
| 8. Dong Yu et al. Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor. 2003 |
| 9. Hee-Jeong Im et al. Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes. 2003 |
| 10. Simona I Chisalita et al. Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells. 2004 |
| 11. Laura Lynch et al. Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells. 2005 |
| 12. Leonard Girnita et al. {beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. 2005 |