ExactAntigen

EGFR antibody review
EGFR antibodies
This is a review about EGFR antibodies, based on 46 published articles using EGFR antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited EGFR antibody. Information in this review (with links to publications) can be searched freely.
ELISA (elisa), flow cytometry (flow), immunocytochemistry (ic), immunohistochemistry (ih), immunoprecipitation (ip), western blot (wb)
CELL SIGNALING TECHNOLOGY    search Cell Signaling Technology EGFR products
includes other brands or spellings
wb    Cell Signaling Technology anti-phospho-EGFR antibodies pY-1068 and pY-992 were used in western blot to study the effect of receptor-type protein-tyrosine phosphatase-κ on epidermal growth factor receptor function.
wb    Cell Signaling Inc. rabbit polyclonal anti-phospho-Tyr1068-EGFR and anti-EGFR antibodies were used in western blot to study the effect of endothelial thrombomodulin on Ca2+ signals and nitric oxide synthesis.
wb    Cell Signaling Technology anti-phospho-EGF receptor (Tyr1068) antibody was used in New Zealand white rabbits renal proximal tubular cell (RPTCs, which were infected with recombinant adenovirus expressing kinase inactive form of human p38) and in western blot to study the role for the effect of p38 kinase on transactivation of the epidermal growth factor receptor in dedifferentiation of renal epithelial cells after oxidant injury.
wb    Cell Signaling Technology anti-EGFR and anti-phospho-EGFR (Tyr845) antibodies were used in human 1HAEo cell line and in western blot to study the link between the PI3K-Akt pathway and the cigarette smoke (CS) -stimulated epidermal growth factor receptor-mediated FRA-1 induction in non-oncogenic HBE cells.
wb    Cell Signaling anti-EGFR and anti-phospho 845-EGFR antibodies were used in human ovarian carcinoma cell lines and in western blot to study the role for endothelin-1-induced prostaglandin E2-EP2, EP4 signaling in regulating vascular endothelial growth factor production and ovarian carcinoma cell invasion.
wb    Cell Signaling Technology phospho-EGFR (Tyr-845, Tyr-1068) antibodies were used in western blot to study phosphorylation of EGFR through zinc-induced Ras activation.
SIGMA-ALDRICH    search Sigma-Aldrich EGFR products
includes other brands or spellings
ih    Sigma EGFR antibody was tested in immunohistochemistry by Human Protein Atlas.
ip, wb    Sigma mouse monoclonal anti-EGFR (clone F4) antibody was used in western blot and immunoprecipition to study the interaction of TSG101 and HRS.
wb    Sigma anti-EGFR antibody was used in western blot to study the dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon.
SANTA CRUZ BIOTECHNOLOGY    search Santa Cruz Biotechnology EGFR products
includes other brands or spellings
ic, wb    Santa Cruz Biotechnology goat polyclonal anti-EGFR antibody was used in immunocytochemistry and western blot to detect EGFR in HeLa cells.
ic, wb    SCBT EGFR antibody against C-terminal region of the EGFR was used in Western blot and immunocytochemistry to investigate the binding of decorin to EGFR.
ic    Santa Cruz Biotechnology polyclonal anti-erbB receptor antibody was used in immunocytochemistry to study that neuregulin-1 enhances motility and migration of human astrocytic glioma cells.
ip, wb    Santa Cruz Biotechnology goat polyclonal EGFR antibody was used in western blot and immunoprecipitation to study L1-mediated activation of EGF receptor kinase.
ip, wb    Santa Cruz Biotechnology rabbit polyclonal anti-EGFR antibody was used in western blot and immunoprecipition to study the interaction of TSG101 and HRS.
ip    Santa Cruz Biotechnology Rabbit polyclonal anti-EGFR antibody (1005) was used in immunoprecipitation to study phosphorylation of EGFR through zinc-induced Ras activation.
ip    Santa Cruz Biotechnology human EGFR antibody was used in western blot and immunoprecipitation to study the activation of EGFR and Akt by Cox2-derived prostaglandin E2.
wb    Santa Cruz Biotechnology rabbit polyclonal antibody against EGF receptor was used in western blot to study the function of a DnaJ domain-containing protein RME-8 in endosomal trafficking.
wb    Santa Cruz Biotechnology anti-EGFR antibody was used in western blot to identify AMSH as an endosome-associated ubiquitin isopeptidase.
wb    Santa Cruz Biotechnology anti-EGFR antibody was used in western blot to study the effect of receptor-type protein-tyrosine phosphatase-κ on epidermal growth factor receptor function.
wb    Santa Cruz Biotechnology anti- ErbB1 (C-18) was used in western blot to examine ErbB1 expression levels in human bladder cancer cell lines 5637 and T24, T-47D breast cancer cells, Wild-type NIH 3T3 clone 7 mouse fibroblasts, as well as NIH 3T3 clone 7 fibroblasts overexpressing ErbB1, ErbB2, ErbB3, or ErbB4.
wb    Santa Cruz Biotechnology goat polyclonal anti-human EGFR antibody was used in human HeLa cells and in western blot to study the role for PKC in controlling traffic pathway for c-Met that operates independently of its degradative pathway.
wb    Santa Cruz Biotechnology rabbit polyclonal anti-autophosphorylated EGFR antibody (RK2) was used in human A431 cells and in western blot to study the role for CIN85 in Cbl-b-mediated down-regulation of receptor tyrosine kinases.
wb    Santa Cruz Biotechnology anti-EGF receptor antibody was used in New Zealand white rabbits renal proximal tubular cell (RPTCs, which were infected with recombinant adenovirus expressing kinase inactive form of human p38) and in western blot to study the role for the effect of p38 kinase on transactivation of the epidermal growth factor receptor in dedifferentiation of renal epithelial cells after oxidant injury.
wb    Santa Cruz Biotechnology rabbit polyclonal anti-EGFR antibody was used in human tTA-HeLa cells and in western blot to study the effect of rab7 activity on epidermal growth factor.
wb    Santa Cruz Biotechnology rabbit anti-EGF receptor was used in western blot to detect EGF receptor in COS1 cells.
wb    Santa Cruz Biotechnology anti-total EGFR antibody was used in Western blot to study the biological function of protein kinase B/Akt phosphorylation.
wb    Santa Cruz Biotechnology phospho-EGFR (Tyr-1173) and EGFR antibodies were used in western blot to study RhoB protective effect from UVB-induced apoptosis in human keratinocytes.
wb    Santa Cruz Biotechnology polyclonal EGFR antibody was used in western blot to study the role of phosphoinositide 3-kinase beta lipid products in LPA-induced Ras activation.
wb    Santa Cruz Biotechnology anti-EGFR antibody was used in western blot to study the production of a soluble ligand (s) of EGFR.
wb    Santa Cruz Biotechnology goat anti-human EGFR antibody (1005-G) was used in western blot to study the role for the sema domain of RON in ligand binding by the full-length receptor..
BD BIOSCIENCES    search BD Biosciences EGFR products
includes other brands or spellings
ic    Transduction Laboratories mouse anti-erbB1 was used in immunocytochemistry to detect the localization of erbB1 in differentiated human airway epithelia.
ip    BD Transduction Laboratories anti-epidermal growth factor receptor antibodies were used in immunoprecipitation to isolate epidermal growth factor receptor from human GTL16 cells.
wb    BD Transduction EGF Receptor antibody was tested in western blot by Abminer.
wb    Transduction Laboratories anti-EGFR antibody was used in western blot to study the interaction of Dok-R and c-Abl.
wb    BD Transduction Laboratories anti-EGFR antibody was used in Western blot to study the biological function of protein kinase B/Akt phosphorylation.
wb    Transduction Laboratories murine monoclonal anti-EGFR antibody was used in western blot to study expression of p53, ErbB1, ErbB2, and Raf-1 in lung cancer.
EMD BIOSCIENCES    search EMD Biosciences EGFR products
includes other brands or spellings
elisa    Oncogene Science EGFR sandwich enzyme-linked immunosorbent assay kit was used to measure serum EGFR concentration.
ic    Oncogene Research Products mouse monoclonal anti-EGFR antibody (alpha-EGFR Ab-5) was used in human tTA-HeLa cells and in immunocytochemistry to study the effect of rab7 activity on epidermal growth factor.
ABCAM    search Abcam EGFR products
includes other brands or spellings
flow    Abcam anti-EGFR antibody was used in flow cytometry to study that N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking.
MILLIPORE    search Millipore EGFR products
includes other brands or spellings
ic, ip, wb    Upstate Biotechnology anti-EGFR antibody was used in western blot, immunoprecipitation and immunocytochemistry to study the mitogenic activity of urokinase-type plasminogen activator which is determined by the dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex.
ic    Upstate Biotechnology mouse monoclonal anti-EGFR antibody (clone LA22) was used in immunocytochemistry to provide evidence for distinct functions of sorting nexin 1 and 2 in protein trafficking by investigating the role for sorting nexin 2 in epidermal growth factor receptor down-regulation.
ip    Upstate Biotechnology monoclonal anti-EGFR antibody LA22 was used in immunoprecipitation to study phosphorylation of EGFR through zinc-induced Ras activation.
wb    Upstate Biotechnology polyclonal EGFR and phospho-EGFR antibodies were used in western blot to study the inhibition EGFR family members in colon and breast cancer cells.
wb    Upstate Biotechnology sheep anti-EGFR polyclonal antibody was used in western blot to study the frequent co-Localization of cox-2 and laminin-5 2 chain at the invasive front of early-stage lung adenocarcinomas.
wb    Upstate rabbit anti-epidermal growth factor receptor (EGFR) and anti-phospho-EGFR antibodies were used in western blot to study the effect of activation of vascular endothelial growth factor receptor 3 on endothelial function and infection.
wb    Upstate Biotechnologies anti-phospho-EGFR antibody pY-1173 was used in western blot to study the effect of receptor-type protein-tyrosine phosphatase-κ on epidermal growth factor receptor function.
INVITROGEN    search Invitrogen EGFR products
includes other brands or spellings
ih    Zymed noclonal mouse anti-EGFR concentrate antibody (clone 31G7) was used in immunohistochemistry to study its status in breast cancer metastases to the central nervous system.
ih    Zymed EGFR antibody was tested in immunohistochemistry by HPA (CAB000035) .
ih    Zymed anti-EGFR antibody was used in immunohistochemistry to study the tissue microarray validation of Epidermal Growth Factor Receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.
ih    Zymed mouse anti-EGFR monoclonal antibody was used in immunohistochemistry to study the frequent co-Localization of cox-2 and laminin-5 2 chain at the invasive front of early-stage lung adenocarcinomas.
ih    Zymed anti-EGFR antibody was used in human HT29 tumors and in immunohistochemistry to study the role for the effect of receptor tyrosine kinase on lymphatic endothelial cells in the therapy of colon cancer lymph node metastasis.
ih    Biosource International anti-phospho-EGFR antibody was used in human HT29 tumors and in immunohistochemistry to study the role for the effect of receptor tyrosine kinase on lymphatic endothelial cells in the therapy of colon cancer lymph node metastasis.
ih    Zymed Laboratories mouse anti–human EGFR, clone 31G7 monoclonal antibody was used in immunohistochemistry to study epidermal growth factor receptor gene and protein and gefitinib sensitivity in non–small-cell lung cancer.
THERMO FISHER SCIENTIFIC    search Thermo Fisher Scientific EGFR products
includes other brands or spellings
ic, wb    NeoMarkers EGFR antibody (Ab-12) was used in Western blot and immunocytochemistry to investigate the binding of decorin to EGFR.
ip    Neomarkers monoclonal anti-EGFR antibody Ab14 was used in immunoprecipitation to study phosphorylation of EGFR through zinc-induced Ras activation.
wb    Lab Vision Epidermal Growth Factor Receptor (EGFR) Ab-5 antibody was tested in western blot by Abminer.
BECKMAN COULTER    search Beckman Coulter EGFR products
includes other brands or spellings
ih    DAKO anti-EGFR antibody was used in immunohistochemistry to study the tissue microarray validation of Epidermal Growth Factor Receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.
ih    Dako anti-EGFR antibody was used in immunohistochemistry to detect EGFR in invasive lobular carcinoma breast tumor sections.
ih    Dako EGFR H11 monoclonal antibody was used in immunohistochemistry to study its expression in paired initial and recurrent glioblastoma multiforme.
ih    Dako EGFR antibody was used in immunohistochemistry to study the activation of EGFR and Akt by Cox2-derived prostaglandin E2.
UPSTATE BIOTECHNOLOGIES INC
wb    Upstate Biotechnologies Inc. anti-phospho-EGF receptor antibody and anti-EGF receptor antibody were used in human hepatic myofibroblasts and in western blot to study the regulation of TFPI-2 expression by thrombin.
VENTANA MEDICAL SYSTEMS
ih    Ventana Medical Systems rabbit polyclonal anti-epidermal growth factor receptor (EGFR) antibody was used in paraffin sections from human breast cancer and in immunohistochemistry to study the role of 17ß-estradiol for down-regulation of Cap43/NDRG1/Drg-1 in human breast cancer cells.


Articles Reviewed
1. Toshiro Niki et al. Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas. 2002
2. Armelle Yart et al. A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. 2002
3. Xiaodan Yu et al. Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228. 2002
4. Weidong Wu et al. Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation. 2002
5. Mihail S Iordanov et al. The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor. 2002
6. Iwona Szymkiewicz et al. CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases. 2002
7. Patricia A Ritch et al. Neuregulin-1 enhances motility and migration of human astrocytic glioma cells. 2003
8. Stephanie Kermorgant et al. Protein kinase C controls microtubule-based traffic but not proteasomal degradation of c-Met. 2003
9. Federica Chiara et al. Mutations in the met oncogene unveil a "dual switch" mechanism controlling tyrosine kinase activity. 2003
10. A M Stark et al. p53, mdm2, EGFR, and msh2 expression in paired initial and recurrent glioblastoma multiforme. 2003
11. Zubin Master et al. Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization. 2003
12. Quan Lu et al. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. 2003
13. Hila Toledano-Katchalski et al. Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon. 2003
14. Torsten O Nielsen et al. Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. 2003
15. Debora Angeloni et al. The soluble sema domain of the RON receptor inhibits macrophage-stimulating protein-induced receptor activation. 2004
16. Teemu T Junttila et al. Identification of patients with transitional cell carcinoma of the bladder overexpressing ErbB2, ErbB3, or specific ErbB4 isoforms: real-time reverse transcription-PCR analysis in estimation of ErbB receptor status from cancer patients. 2003
17. Véronique Neaud et al. Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism. 2004
18. Rafique Islam et al. Activation of EGF receptor kinase by L1-mediated homophilic cell interactions. 2004
19. Anuradha Gullapalli et al. A role for sorting nexin 2 in epidermal growth factor receptor down-regulation: evidence for distinct functions of sorting nexin 1 and 2 in protein trafficking. 2004
20. Matthew Wherlock et al. Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase. 2004
21. Linda M Shearwin-Whyatt et al. N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking. 2004
22. John McCullough et al. AMSH is an endosome-associated ubiquitin isopeptidase. 2004
23. Nichon L Grupka et al. Epidermal growth factor receptor status in breast cancer metastases to the central nervous system. Comparison with HER-2/neu status. 2004
24. Francesca Spinella et al. Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion. 2004
25. Vanesa Gregorc et al. Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancer. 2004
26. Daniel G Hayward et al. The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer. 2004
27. Stefan Kippenberger et al. Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor. 2005
28. Minji Jo et al. Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator. 2005
29. Hu Xu et al. Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells. 2005
30. Michelle T Fodero-Tavoletti et al. Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization. 2005
31. Shougang Zhuang et al. p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. 2005
32. Chang Han et al. Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt. 2005
33. Federico Cappuzzo et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. 2005
34. Xuefeng Zhang et al. Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. 2005
35. Jing-Xu Zhu et al. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. 2005
36. Monique David-Dufilho et al. Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II. 2005
37. Martine Girard et al. The DnaJ-domain protein RME-8 functions in endosomal trafficking. 2005
38. Yiru Xu et al. Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function. 2005
39. Bruno Canguilhem et al. RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling. 2005
40. Brian P Ceresa et al. rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome. 2006
41. Paola D Vermeer et al. erbB1 functions as a sensor of airway epithelial integrity by regulation of protein phosphatase 2A activity. 2006
42. Qin Zhang et al. A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression. 2006
43. Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006
44. Abbas Fotovati et al. 17Beta-estradiol induces down-regulation of Cap43/NDRG1/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells. 2006
45. Anja Persson et al. A human protein atlas based on antibody proteomics. 2006
46. Robert B Rebhun et al. Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis. 2006


2008©ExactAntigen home | browse | about