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Bcl 2 antibody review
BCL2 antibodies
This is a review about Bcl 2 antibodies, based on 63 published articles using Bcl 2 antibodies in western blot, immunohistochemistry, immunoprecipitation, immunocytochemistry, and other immunological technologies. It is aimed to help ExactAntigen visitors find the most suited Bcl 2 antibody. Information in this review (with links to publications) can be searched freely.
flow cytometry (flow), immunocytochemistry (ic), immunohistochemistry (ih), immunoprecipitation (ip), western blot (wb)
CELL SIGNALING TECHNOLOGY    search Cell Signaling Technology BCL2 products
includes other brands or spellings
wb    Cell Signaling anti-Bcl-2 antibody was used in western blot to study the effect of adrenomedullin on myocardial infarction and apoptosis after ischemia and reperfusion.
wb    Cell Signaling Technology anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in U373 cells with human MEKK3 stable transfection.
wb    Cell Signaling rabbit anti-phospho-Bcl-2 antibody was used in western blot to detect phospho-Bcl-2 in human ejaculate spermatozoa.
wb    Cell Signaling Technology anti-Bcl-2 antibody was used in western blot to study the relationship between FPR expression and the biologic behavior of glioma cells.
wb    Cell Signaling Bcl-2 antibody was used in western blot to study apoptotic cell death in prostate cancer caused by androgen receptor silencing.
SIGMA-ALDRICH    search Sigma-Aldrich BCL2 products
includes other brands or spellings
wb    Sigma anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in BdGBM cells.
SANTA CRUZ BIOTECHNOLOGY    search Santa Cruz Biotechnology BCL2 products
includes other brands or spellings
ip, wb    Santa Cruz Biotechnology anti-Bcl-2 antibody was used in human PC-3 cells and in western blot and immunoprecipitation to study the role of IGFBP-3 for TNF- -induced apoptosis.
wb    Santa Cruz Biotechnology polyclonal N19 Bcl2 antibody was used in western blot to study cell death protection by cytosolic prion protein in human primary neurons.
wb    Santa Cruz Biotechnology anti-BCL-2 antibody was used in western blot to study that PIM-2 kinase phosphorylates BAD on Serine 112 and reverses BAD-induced cell death.
wb    Santa Cruz Biotechnology mouse anti-bcl-2 antibody was used in western blot to provide another molecular mechanism consistent with the hypothesis that 15-LOX-1 may exert anti-inflammatory effects by inhibiting TrxR.
wb    Santa Cruz Biotechnology anti-Bcl-2 antibody SC-7382 was used in western blot to study the effect of p53-independent NOXA induction on apoptotic resistance of malignant melanomas.
wb    Santa Cruz Biotechnology mouse monoclonal anti-Bcl-2 antibody sc-7382 was used in western blot to study the expression of proapoptotic factor Nix and Bcl-xL during terminal erythroid differentiation.
wb    Santa Cruz Biotechnology mouse anti-human Bcl-2 antibody was used in western blot to detect Bcl-2 in LNCaP and PC-3 cells.
wb    Santa Cruz Biotechnology anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in wild-type Jurkat and Jurkat cells stably transfected with Bcl-2 or vector control cells.
wb    Santa Cruz Biotechnology mouse monoclonal anti-Bcl2 antibody Bcl-2 was used in human T-cell lymphoblastic leukemia cell line CCRF-HSB-2 cells and in western blot to study the taxol-induced caspase-10-dependent apoptosis.
wb    Santa Cruz Biotechnology mouse monoclonal anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in MCF-7 cells treated with drugs.
wb    Santa Cruz Biotechnology Bcl-2 antibody was used in western blot to study apoptotic induction by apicidin in human Bcr-Abl-positive leukemia cells.
wb    Santa Cruz Biotechnology polyclonal anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in Jurkat cells treated with phytosphingosine.
wb    Santa Cruz Biotechnology anti-Bcl-2 antibody was used in human Jurkat cells and in western blot to study the effect of granzyme B on Mcl-1.
wb    Santa Cruz anti-Bcl-2 antibody was used in western blot to study the functional link between FGFR2 signaling and Cbl-mediated alpha-5-integrin expression resulting in altered cell attachment and apoptosis in osteoblasts.
wb    Santa Cruz Biotechnology mouse anti-BCL-2 antibody was used in western blot to study the CSF-independent human macrophages survival.
wb    Santa Cruz Biotechnology Bcl-2 antibody was used in western blot to study the role of Cyr61 in endometrial tumorigenesis.
wb    Santa Cruz Biotechnology mouse monoclonal anti-Bcl-2 (100) antibody was used in western blot to study the selective induction of apoptosis by synthetic retinoid CD437 in human lung cancer cells.
wb    SCBT anti-Bcl-2 antibody was used in western blot to study the induction of neuroblastoma cell apoptosis by TrkA.
wb    SCBT Bcl-2 antibody was used in western blot to study the effect of Gadd45a on Bim.
wb    Santa Cruz Biotechnology monoclonal antibody which recognizes Bcl-2 was used in western blot to study the functions of human SCO1 and SCO2 in copper delivery to cytochrome c oxidase.
wb    Santa Cruz Biotechnology monoclonal Bcl-2 antibody was used in western blot to study the effect on BAD phosphorylation and Bcl-2 association by Raf-1 phosphorylation.
R & D SYSTEMS    search R & D Systems BCL2 products
includes other brands or spellings
flow, wb    R&D Bcl-2 and phospho-Bcl-2 serine 70 antibodies were used in western blot and flow cytometry to study Bcl-2 rescues of mitochondrial apoptosis.
BD BIOSCIENCES    search BD Biosciences BCL2 products
includes other brands or spellings
flow    BD Biosciences FITC-anti-bcl-2 monoclonal antibody was used in flow cytometry to study a 10-aa-long sequence in SLP-76 upstream of the Gads binding site which is essential for T cell development and function.
ic    BD PharMingen monoclonal anti-bcl-2 antibody was used in human islets and in immunocytochemistry to study the capability of GLP-1 to preserve viability and function of freshly isolated human islets.
ih, wb    BD Transduction Laboratories monoclonal antibody to Bcl-2 was used in western blot in the study of fibronectin protecting prostate cancer cells from tumor necrosis factor-alpha-induced aoptosis via the AKT/Survivin pathway.
wb    BD Transduction Bcl-2 antibody was tested in western blot by Abminer.
wb    BD Biosciences anti-Bcl-2 antibody was used in western blot to study the effects of TL1A-induced NF- B and c-IAP2 on DR3-mediated apoptosis in TF-1 cells.
wb    BD Biosciences anti-Bcl-2 antibody was used in western blot to study the function of protein phosphatase subunit G5PR in B cell receptor–induced apoptosis.
wb    PharMingen monoclonal anti-Bcl-2 antibody was used in western blot to study NADUO as an ischemia/reperfusion-regulated gene in cardiomyocytes.
wb    BD PharMingen anti–bcl-2 was used in western blot to detect bcl-2 in Jurkat cells.
wb    Pharmingen antihuman Bcl-2 antibody was used in western blot to study the different antiapoptotic pathways between wild-type and mutated FLT3.
wb    Becton Dickinson mouse anti-Bcl-2 antibody was used in western blot to study 7-Kchol induces oxidative stress and apoptotic events in human aortic smooth muscle cells.
wb    Transduction Labs mouse monoclonal anti-Bcl-2 antibody was used in western blot to study the possible correlation of the antitumor activity of fibroblast growth factors (FGFs) for medulloblastoma with FGF receptor expression and tumor variant.
MILLIPORE    search Millipore BCL2 products
includes other brands or spellings
wb    Upstate Biotechnologies anti-Bcl-2 antibody was used in western blot to study dendritic cell apoptosis in the maintenance of immune tolerance.
INVITROGEN    search Invitrogen BCL2 products
includes other brands or spellings
wb    BIOSOURCE International anti-Bcl-2 antibody was used in western blot to study the functional expression of the interleukin-11 receptor alpha-Chain and evidence of antiapoptotic effects in human colonic epithelial cells.
THERMO FISHER SCIENTIFIC    search Thermo Fisher Scientific BCL2 products
includes other brands or spellings
wb    Lab Vision bcl-2alpha antibody was tested in western blot by Abminer.
wb    NeoMarkers anti-Bcl-2 antibody was used in human T-cell leukemia cell lines and in western blot to study the effect of Jak-Stat pathway on cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells.
BECKMAN COULTER    search Beckman Coulter BCL2 products
includes other brands or spellings
flow, wb    DAKO mouse anti-human Bcl-2 antibody was used in western blot and flow cytometry to analyze the expression of Bcl-2 in high density, CD27-depleted tonsil B lymphocytes and lysates of CD40-activated human follicular B cells from human tonsil tissue of 3- to 15-year-old donors.
ic    DakoCytomation mouse monoclonal FITC-conjugated anti–Bcl-2 antibody was used in immunocytochemistry to study interleukin 7 effects on T cell acute lymphoblastic leukemia cells.
ih    DakoCytomation BCL2 antibody was tested in immunohistochemistry by HPA (CAB000003) .
ih    Dako antibody against BCL2 was used in immunohistochemistry to identify the human germinal center-associated lymphoma (HGAL) in gene-expression profiling studies of diffuse large B-cell lymphoma (DLBCL).
ih    DAKO anti-bcl-2 antibody was used in immunohistochemistry to study the tissue microarray validation of Epidermal Growth Factor Receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology.
ih    DAKO anti-bcl-2 antibody clone 124 was used in paraffin sections from human urothelial bladder carcinomas and in immunohistochemistry to study the role of TIMP-2 in human urothelial cancer.
ih    DAKO monoclonal Bcl-2 antibody (clone 124) was used in immunohistochemistry to detect Bcl-2 expression in human primary mediastinal (thymic) B-cell lymphoma (PMBL).
ih    DAKO anti-BclII antibody was used in immunohistochemistry to detect BclII in normal lung, benign lesions, preinvasive lesions, low-grade tumors and invasive lung carcinoma.
ih    Dako anti-Bcl-2 antibody (124) was used in immunohistochemistry to study the implications of expression of a panel of oncogenic proteins (Bcl-2, Bcl-6, and c-Myc) and p53 for predicting clinical outcome, particularly overall survival, in immunocompetent individuals with primary CNS DLBCL.
ih    DAKO bcl-2 antibody (clone 124) was used in immunohistochemistry to study the upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis.
ih    DAKO mouse monoclonal antihuman Bcl-2 antibody was used in immunohistochemistry to study the possible spatial and temporal relationships among GATA-6 expression, cell proliferation, apoptosis, and the apoptosis-related proteins Bcl-2 and Bax during human fetal testicular development.
wb    Dako mouse monoclonal anti-Bcl-2 antibody was used in western blot to study the mechanism by which the EBNA3 proteins gain access to the antigen-processing pathways in infected cells although they were degraded by purified 20S proteasomes in vitro.
wb    DAKO anti-Bcl-2 antibody M0887 was used in human HeLa cells and in western blot to study the role of CDIR for apoptosis.
wb    DAKO anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in U937 cells incubated for 24 h with 1-mM SB or 2-µM SAHA ± 100-ng/ml TRAIL in the absence or presence of the pan-caspase inhibitor BOC-D-fmk.
wb    Dako mouse monoclonal anti-Bcl-2 antibody was used in western blot to detect Bcl-2 in K562-R, LAMA-R and their parental counterparts.
wb    DAKO mouse anti-human Bcl2 (clone 124, M0887) was used in western blot to study the suppression of p53 and c-myc and regulation of apopotosis by fibronectin in human primary cells.
wb    Dako mouse monoclonal Bcl-2 antibody was used in western blot to study the interactions between pharmacological MEK1/2 inhibitors and STI571 in Bcr/Abl-positive human leukemia cells.
BEIJING ZHONGSHAN BIOLOGICAL TECHNOLOGY
ih    Beijing Zhongshan Biological Technology mouse monoclonal bcl-2 antibody was used in immunohistochemistry to study gastrin, somatostatin, bcl-2, and bax expression in large intestine carcinoma.
CAMBRIDGE RESEARCH BIOCHEMICALS
ih    Cambridge Research Biochemicals monoclonal anti-human Bcl-2 antibody was used in immunohistochemistry to detect Bcl-2 protein in transgenic mice overexpressing human Bcl-2.
CN BIOSCIENCES
wb    CN Biosciences anti-Bcl-2 antibody was used in western blot to study the induction a Fas-associated death domain-dependent type II apoptotic pathway by tissue inhibitor of metalloproteinase-3.
WAKO PURE CHEMICAL INDUSTRIES
wb    Wako Pure Chemical Industries monoclonal anti-human Bcl-2 antibody was used in western blot to study the involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis which was induced by β-hydroxyisovalerylshikonin.


Articles Reviewed
1. Yvonne L Kapila et al. The heparin-binding domain and V region of fibronectin regulate apoptosis by suppression of p53 and c-myc in human primary cells. 2002
2. Chunrong Yu et al. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells. 2002
3. Sabine M Duplan et al. Antitumor activity of fibroblast growth factors (FGFs) for medulloblastoma may correlate with FGF receptor expression and tumor variant. 2002
4. Mark Bond et al. Tissue inhibitor of metalloproteinase-3 induces a Fas-associated death domain-dependent type II apoptotic pathway. 2002
5. Shi-Yong Sun et al. The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells. 2002
6. Roopmathy Rajah et al. Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation. 2002
7. Ksenya Shchors et al. Cell death inhibiting RNA (CDIR) derived from a 3'-untranslated region binds AUF1 and heat shock protein 27. 2002
8. Makoto Kamachi et al. Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway. 2002
9. Stefano A Pileri et al. Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors OCT-2, BOB.1, and PU.1 in the absence of immunoglobulins. 2003
10. Chung-Che Chang et al. Expression of p53, c-Myc, or Bcl-6 suggests a poor prognosis in primary central nervous system diffuse large B-cell lymphoma among immunocompetent individuals. 2003
11. Wulin Aerbajinai et al. The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation. 2003
12. Ilkka Ketola et al. Transcription factor GATA-6, cell proliferation, apoptosis, and apoptosis-related proteins Bcl-2 and Bax in human fetal testis. 2003
13. Chih-Cheng Yang et al. Bcl-xL mediates a survival mechanism independent of the phosphoinositide 3-kinase/Akt pathway in prostate cancer cells. 2003
14. Kazuo Kato et al. Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. 2003
15. Pierre-François Cartron et al. Nonredundant role of Bax and Bak in Bid-mediated apoptosis. 2003
16. Alexandra Giatromanolaki et al. Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis. 2003
17. Yosuke Minami et al. Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia. 2003
18. Leng Wen et al. TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells. 2003
19. Xavier Roucou et al. Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons. 2003
20. Bin Yan et al. The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. 2003
21. Loredana Farilla et al. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. 2003
22. Torsten O Nielsen et al. Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. 2003
23. Moon-Taek Park et al. Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells. 2003
24. Mara Fornaro et al. Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway. 2003
25. María Victoria Sánchez-Gómez et al. Caspase-dependent and caspase-independent oligodendrocyte death mediated by AMPA and kainate receptors. 2003
26. June-Won Cheong et al. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells. 2003
27. Patricia K A Mongini et al. Role of complement-binding CD21/CD19/CD81 in enhancing human B cell protection from Fas-mediated apoptosis. 2003
28. Hariklia Gakiopoulou et al. Tissue inhibitor of metalloproteinase-2 as a multifunctional molecule of which the expression is associated with adverse prognosis of patients with urothelial bladder carcinomas. 2003
29. Ajoy K Samanta et al. Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB. 2004
30. Stephan Kiessling et al. Functional expression of the interleukin-11 receptor alpha-chain and evidence of antiapoptotic effects in human colonic epithelial cells. 2004
31. Roberto R Rosato et al. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells. 2003
32. Chi-Hsiao Yeh et al. Differential-display polymerase chain reaction identifies nicotinamide adenine dinucleotide-ubiquinone oxidoreductase as an ischemia/reperfusion-regulated gene in cardiomyocytes. 2004
33. Alberto Ballestrero et al. Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells. 2004
34. Saveria Aquila et al. Estrogen receptor (ER)alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway. 2004
35. Jie Han et al. Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events. 2004
36. Julien Mazieres et al. Loss of RhoB expression in human lung cancer progression. 2004
37. Margaret K Yu et al. Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes. 2004
38. Daniel Broderick Longley et al. The roles of thymidylate synthase and p53 in regulating Fas-mediated apoptosis in response to antimetabolites. 2004
39. Yun Dai et al. A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2. 2004
40. Scot C Leary et al. Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase. 2004
41. Yutaka Masuda et al. Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin. 2004
42. Jian-Zhong Qin et al. p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. 2004
43. Joao T Barata et al. Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. 2004
44. Soo-Jung Park et al. Taxol induces caspase-10-dependent apoptosis. 2004
45. Wenwen Chien et al. Cyr61 suppresses growth of human endometrial cancer cells. 2004
46. Eric Pedruzzi et al. NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells. 2004
47. Jia-Ding Mao et al. Correlation between expression of gastrin, somatostatin and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma. 2005
48. Yasodha Natkunam et al. Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation. 2005
49. Karim Kaabeche et al. Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation. 2005
50. Chiou-Feng Lin et al. Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation. 2005
51. Xinbo Liao et al. Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer. 2005
52. Robert Touitou et al. Epstein-Barr virus EBNA3 proteins bind to the C8/alpha7 subunit of the 20S proteasome and are degraded by 20S proteasomes in vitro, but are very stable in latently infected B cells. 2005
53. Shenghao Jin et al. p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association. 2005
54. Tong Tong et al. Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria. 2005
55. Ye Zhou et al. Formylpeptide receptor FPR and the rapid growth of malignant human gliomas. 2005
56. Jean-François Lavoie et al. TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism. 2005
57. Yan Xing et al. Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis. 2005
58. Iwao Komuro et al. Catalase plays a critical role in the CSF-independent survival of human macrophages via regulation of the expression of BCL-2 family. 2005
59. Lalit Kumar et al. A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function. 2005
60. Min Chen et al. Dendritic cell apoptosis in the maintenance of immune tolerance. 2006
61. Sylvia M Major et al. AbMiner: a bioinformatic resource on available monoclonal antibodies and corresponding gene identifiers for genomic, proteomic, and immunologic studies. 2006
62. Mariko Tomita et al. Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. 2006
63. Anja Persson et al. A human protein atlas based on antibody proteomics. 2006


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