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| name: | Monoclonal Anti-S-100 (beta-Subunit) antibody produced in mouse |
| cat_no: | S2657 |
| gene id: | human S100B(6285); rat S100b(25742) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | clone SH-B4, ascites fluid |
| storage temp.: | -20C |
| storage: | -20C |
| antibody form: | ascites fluid |
| shipped in: | dry ice |
| species reactivity: | human, bovine, pig, rabbit, goat, sheep, canine, feline, rat |
| application(s): | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using protease-digested, formalin-fixed, paraffin-embedded human tongue sections; dot blot: suitable using denatured-reduced preparations; indirect ELISA: suitable |
| immunogen: | bovine brain S-100b |
| unspsc_code: | 12352203 |
| wgk: | 3 |
| mdl_no: | MFCD00162834 |
| clone: | SH-B4 |
| isotype: | IgG1 |
| specificity: | Recognizes an epitope located on the beta chain (i.e. in S-100a and S-100b) but not on the alpha chain of S-100 (i.e. in S-100a and S-100ao). In ELISA, recognition of S-100 subunit by clone SH-B4 is Ca2+-dependent. The product does not react with other members of the EF-hand family such as, calmodulin, parvalbumin, intestinal calcium-binding protein and myosin light chain. In immunohistochemistry, the antibody detects normal and neoplastic S-100 beta subunit-containing cells (e.g. Schwann cells, chondrocytes, melanocytes, and melanotic tumors) in protease-digested, formalin-fixed, paraffin-embedded tissues. |
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