| request information: |
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| name: | alpha-Synuclein A53T human |
| cat_no: | S1071 |
| gene id: | human SNCA(6622) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | recombinant, expressed in Escherichia coli, N-terminal histidine tagged, >=90% (SDS-PAGE), lyophilized powder |
| storage temp.: | -20C |
| storage: | -20C |
| form: | lyophilized powder |
| shipped in: | dry ice |
| unspsc_code: | 51000000 |
| wgk: | 3 |
| mdl_no: | MFCD06411759 |
| biochem/physiol actions: | A point mutation in the alpha-synuclein gene, A53T (Ala53-Thr), is linked to familial Parkinson's disease. Mice expressing A53T human alpha-synuclein, but not wild-type or the A30P variants, develop adult-onset neurodegenerative disease with a progressive motoric dysfunction leading to death. |
| purity: | >=90% (SDS-PAGE) |
| assay: | >=90% (SDS-PAGE) |
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more information: | company product webpage |
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