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| name: | Monoclonal Anti-Ryanodine Receptor antibody produced in mouse |
| cat_no: | R129 |
| gene id: | rat Ryr2(84025); human RYR2(6262); mouse Ryr2(20191); rat Ryr1(114207); human RYR1(6261); mouse Ryr1(20190) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | clone 34C, ascites fluid |
| storage temp.: | -20C |
| storage: | -20C |
| physical form: | Diluted ascites fluid containing 0.05% sodium azide |
| antibody form: | ascites fluid |
| shipped in: | dry ice |
| species reactivity: | chicken, human, bovine, sheep, canine, rat, mouse, rabbit, frog, fish |
| application(s): | immunohistochemistry (frozen sections): 1:1,000; immunoblotting: 1:5,000 |
| immunogen: | partially purified chicken pectoral muscle ryanodine receptors (RyR) |
| unspsc_code: | 12352203 |
| mdl_no: | MFCD00282461 |
| clone: | 34C |
| isotype: | IgG1 |
| mol wt: | antigen mol wt 565 kDa (non-mammalian vertebrates, doublet at 565 kDa representing the alpha and beta isoforms) |
| specificity: | The antibody reacts strongly with RyR-1 (expressed predominantly in skeletal muscle and areas of the brain; also known as the alpha isoform) and RyR-2 (expressed predominantly in the heart muscle, but also found in stomach, endothelial cells and diffuse areas of the brain; also known as the beta isoform). In immunohistochemistry, the antibody stains are consistent with the endoplasmic reticulum localization of the receptor in rat hippocampus. |
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more information: | company product webpage |
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