| name: | Monoclonal Anti-P-Glycoprotein (MDR) antibody produced in mouse |
| cat_no: | P7965 |
| gene id: | human ABCB1(5243) |
| brand: | SIGMA |
| link: | www.sigmaaldrich.com/catalog/search ... |
| prod_type: | Chemical |
| name_suffix: | clone F4, ascites fluid |
| storage temp.: | -20C |
| storage: | -20C |
| unspsc_code: | 12352203 |
| shipped in: | dry ice |
| antibody form: | ascites fluid |
| application(s): | immunoprecipitation: suitable;indirect ELISA: suitable;radioimmunoassay: suitable using cell-surface RIA;immunohistochemistry (frozen sections): suitable;immunoblotting: suitable;immunocytochemistry: suitable;immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500 using human kidney sections |
| species reactivity: | human, hamster |
| immunogen: | mixture of human and hamster drug-resistant whole cells and crude plasma membranes. |
| mdl_no: | MFCD00282355 |
| wgk: | 3 |
| mol wt: | antigen mol wt 170-180 kDa |
| specificity: | The antibody recognizes an epitope located in the amino terminal half of P-glycoprotein (Pgp), at the third extracellular loop of the molecule. The epitope is resistant to formalin fixation and periodate oxidation. The antibody detects specifically human MDR1 P-glycoprotein, but does not appear to recognize the human MDR3 product, nor the mouse mdr1a, mdr1b or the mdr3 P-glycoprotein. |
| clone: | F4 |
| isotype: | IgG1 |
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more information: | company product webpage |
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