| request information: | |
| name: | Anti-Presenilin-1 (S182) antibody produced in rabbit |
| cat_no: | P7854 |
| gene id: | mouse Psen1(19164); human PSEN1(5663); rat Psen1(29192) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | IgG fraction of antiserum, buffered aqueous solution |
| storage temp.: | -20C |
| storage: | -20C |
| form: | buffered aqueous solution |
| physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| antibody form: | IgG fraction of antiserum |
| shipped in: | dry ice |
| species reactivity: | human, mouse, rat, Xenopus |
| application(s): | microarray: suitable; immunoblotting: 1:10,000 using whole cell extract of PC12 rat adrenal pheochromocytoma cell line; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100 using methacarn-fixed, formic acid-treated sections of Alzheimer's Disease (AD) brain |
| immunogen: | synthetic peptide corresponding to the C-terminal of human presenilin-1 (amino acids 450-467 with N-terminally added lysine) conjugated to KLH. |
| unspsc_code: | 12352203 |
| wgk: | 3 |
| mdl_no: | MFCD02097229 |
| specificity: | Specific for presenilin 1 (not found in presenilin 2) and is identical in mouse, rat, and Xenopus. By immunoblotting, the antibody reacts with presenilin 1 (PS1, S182) and with the PS1 cleavage product. |
order or more information: | company product webpage |