| request information: |
|
| name: | Plasminogen from human plasma |
| cat_no: | P5661 |
| gene id: | human PLG(5340) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | lyophilized powder, >=2 units/mg protein, suitable for streptokinase determination by clot formation procedure |
| storage temp.: | 2-8C |
| storage: | 2-8C |
| form: | lyophilized powder |
| physical form: | Lyophilized powder containing NaCl, EDTA, lysine and Tris buffer |
| syns: | Profibrinolysin |
| wgk: | 3 |
| mdl_no: | MFCD00131922 |
| mol wt: | mol wt 90 kDa |
| biochem/physiol actions: | Plasminogen is the inactive precursor of the protease plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration. Plasmin cleaves fibrin/fibrinogen and blood coagulation factors V/Va and VIII/VIIIa. It activates matrix metalloproteinases by cleaving the inactive proenzymes. It is also involved in the activation of some growth factors, such as vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-beta). |
| iod_codes: | B |
| eg_ec_no: | 232-641-9 |
order or
more information: | company product webpage |
|