| request information: |
|
| name: | Monoclonal Anti-p300/CBP antibody produced in mouse |
| cat_no: | P2859 |
| gene id: | human PCAF(8850); rat Pcaf(301164); mouse Pcaf(18519) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | ~2 mg/mL, clone NM11, purified immunoglobulin, buffered aqueous solution |
| storage temp.: | -20C |
| storage: | -20C |
| form: | buffered aqueous solution |
| physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| antibody form: | purified immunoglobulin |
| shipped in: | dry ice |
| species reactivity: | human, monkey, mink, mouse, rat |
| application(s): | immunoprecipitation1,2: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunohistochemistry (frozen sections): suitable; microarray: suitable; immunocytochemistry: suitable; immunoblotting1,2: 10-20 mug/mL using human 293 embryonal kidney cells |
| immunogen: | native human p300. |
| syns: | Anti-CREB Binding Protein |
| unspsc_code: | 12352203 |
| wgk: | 3 |
| mdl_no: | MFCD02097119 |
| clone: | NM11 |
| isotype: | IgG1 |
| mol wt: | antigen mol wt 300 kDa |
| specificity: | Reacts specifically with both p300 and CBP but not with the related p270 molecule. The epitope recognized by the antibody resides within the 21 amino acid stretch spanning amino acids 2071-2091 near the CBP C-terminus. CBP and p300 differ by three noncontiguous residues within this 21 amino acid region, a difference that does not detectably affect the reactivity of the antibody. |
| concentration: | ~2 mg/mL |
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more information: | company product webpage |