| request information: |
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| name: | Orexin A human, rat, mouse |
| cat_no: | O6012 |
| gene id: | human HCRT(3060); mouse Hcrt(15171); rat Hcrt(25723) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | >=97% (HPLC) |
| storage temp.: | -20C |
| storage: | -20C |
| syns: | Hypocretin 1 |
| unspsc_code: | 12352209 |
| wgk: | 3 |
| mdl_no: | MFCD01635374 |
| linear_formula: | C152H243N47O44S4 |
| empform: | C152H243N47O44S4 |
| empform_search: | C152H243N47O44S4 |
| fw: | 3561.10 |
| biochem/physiol actions: | Orexins (hypocretins) comprise a family of hypothalamic peptides that are involved in the initiation of sleep and in feeding behavior. Orexin A stimulates food intake through activation of the OX1 receptor. Orexin B activates OX2 receptors. Both OX1 and OX2 receptors are involved in maintaining arousal. OX2 receptors appear to be inhibitory autoreceptors on orexin-containing neurons. |
| purity: | >=97% (HPLC) |
| assay: | >=97% (HPLC) |
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more information: | company product webpage |