| cat_no: | | N6909 |
| name: | | Neurturin human |
| gene id: | | human NRTN(4902) |
| link: | | www.sigmaaldrich.com/catalog/search ... |
| analysis note: | | The biological activity is measured by its ability to bind recombinant human GFRalpha2/Fc. |
| assay: | | >95% (SDS-PAGE) |
| biochem/physiol actions: | | Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways. Human and mouse NTN share 91% sequence identity. |
| brand: | | SIGMA |
| form: | | lyophilized powder |
| mdl_no: | | MFCD01867712 |
| mol wt: | | predicted mol wt ~14 kDa by SDS-PAGE (reducing); monomer calculated mol wt ~12.5 kDa |
| name_suffix: | | >95% (SDS-PAGE), recombinant, expressed in Escherichia coli, lyophilized powder |
| physical form: | | Lyophilized from a 0.2 mum filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin. |
| prod_type: | | Chemical |
| purity: | | >95% (SDS-PAGE) |
| recombinant: | | expressed in Escherichia coli |
| storage: | | -20C |
| storage temp: | | -20C |
| syns: | | NRTN; NTN |
| total impurities: | | Endotoxin, tested |
| unspsc_code: | | 12352207 |
| wgk: | | 3 |
| more information: | | company product webpage |