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| name: | Neurotrophin-4 human |
| cat_no: | N1780 |
| gene id: | human NTF5(4909) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | >=97% (SDS-PAGE), recombinant, expressed in Sf21 cells, lyophilized powder, cell culture tested |
| storage temp.: | -20C |
| storage: | -20C |
| form: | lyophilized powder |
| physical form: | Lyophilized from a 0.2 mum filtered solution in phosphate buffered saline, pH 7.4, containing 50 mug bovine serum albumin per 1 mug of cytokine. |
| syns: | NT-4 |
| unspsc_code: | 12352207 |
| wgk: | 3 |
| mdl_no: | MFCD00212405 |
| mol wt: | mol wt 14 kDa |
| biochem/physiol actions: | Neurotrophin-4 (also called NT-4/5 or NT-5) is a 14 kDa member of the neurotrophin family. NT-4 shares 95% sequence homology between human and rat. NT-4 from human, rat, and Xenopus are active on chick dorsal root ganglia. NT-4 is expressed in many tissues and major brain regions. NT-4 promotes survival and differentiation of various cells in culture including spinal neuons, basal forebrain cholinergic neurons, hippocampal neurons, cerebellar granule cells, embryonic dopaminergic neruons of mesencephalon, noradrenergic neurons of the locus coeruleus, dopaminergic, GABAergic, and serotoninergic neurons of the substantia nigra, and embryonic trigeminal and jugular neurons. |
| purity: | >=97% (SDS-PAGE) |
| assay: | >=97% (SDS-PAGE) |
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more information: | company product webpage |
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