| cat_no: | M8177 |
| name: | Monoclonal Anti-p38 MAP Kinase, Activated (Diphosphorylated p38) antibody produced in mouse |
| gene id: | rat Mapk14(81649); mouse Mapk14(26416); human MAPK14(1432) |
| link: | www.sigmaaldrich.com/catalog/search ... |
| antibody form: | purified immunoglobulin |
| application: | immunocytochemistry: suitable; microarray: suitable; indirect ELISA: suitable; immunoblotting: 1 mug/mL using whole cell extract from a rat fibroblast cell line, Rat1, activated with sorbitol |
| brand: | SIGMA |
| clone: | P38-TY |
| concentration: | ~2 mg/mL |
| form: | buffered aqueous solution |
| immunogen: | synthetic peptide HTDDEMpTGpYVATR corresponding to the phosphorylated form of p38 MAP kinase activation loop. |
| isotype: | IgG2a |
| mdl_no: | MFCD00803556 |
| name_suffix: | ~2 mg/mL, clone P38-TY, purified immunoglobulin, buffered aqueous solution |
| physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| prod_type: | Chemical |
| shipped in: | dry ice |
| species reactivity: | human, mouse, rat |
| specificity: | Reacts specifically with the active diphosphorylated form of p38 MAP kinase and its closely related isoforms. Does not recognize the non-phosphorylated and monophosphorylated forms of the p38 MAP kinase molecule, or the non-phosphorylated, monophosphorylated and diphosphorylated forms of JNK and ERK-MAP kinases. The epitope recognized by the antibody contains the phosphorylated threonine and tyrosine residues within the regulatory site of active p38 MAP kinase (Thr180-Gly181-Tyr182). |
| storage: | -20C |
| storage temp: | -20C |
| syns: | Anti-MAP Kinase, p38, Activated |
| unspsc_code: | 12352203 |
| wgk: | 3 |