| cat_no: | | H7660 |
| name: | | Heregulin-beta1 (EGF Domain) human |
| gene id: | | human NRG1(3084) |
| link: | | www.sigmaaldrich.com/catalog/search ... |
| analysis note: | | The biological activity is measured by its ability to stimulate the proliferation of human MCF-7 cells grown under serum-free conditions. |
| assay: | | >=98% (SDS-PAGE and HPLC) |
| biochem/physiol actions: | | Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways. |
| brand: | | SIGMA |
| form: | | lyophilized powder |
| mdl_no: | | MFCD03457066 |
| mol wt: | | predicted mol wt 8 kDa |
| name_suffix: | | >=98% (SDS-PAGE and HPLC), recombinant, expressed in Escherichia coli, lyophilized powder |
| physical form: | | Lyophilized from a 0.2 mum filter with 2.5 mg bovine serum albumin. |
| prod_type: | | Chemical |
| purity: | | >=98% (SDS-PAGE and HPLC) |
| recombinant: | | expressed in Escherichia coli |
| s_codes: | | 22-24/25 |
| storage: | | -20C |
| storage temp: | | -20C |
| syns: | | HRG-beta1 |
| total impurities: | | Endotoxin, tested |
| unspsc_code: | | 12352207 |
| wgk: | | 3 |
| more information: | | company product webpage |