| cat_no: | | H0786 |
| name: | | Heregulin-beta, EGF Domain human |
| gene id: | | human NRG1(3084) |
| link: | | www.sigmaaldrich.com/catalog/search ... |
| analysis note: | | Stimulates tyrosine phosphorylation of the ErbB-3/HER-3 receptor.; The biological activity is measured by its ability to activate the c-ErbB3/HER-3 receptor in treated MCF-7 cells. |
| assay: | | ~80% (SDS-PAGE) |
| biochem/physiol actions: | | Growth factor ligand for ErbB3 and ErbB4 receptor tyrosine kinases. The binding of HRG results in receptor dimerization and receptor trans-autophosphorylation. The phosphorylated receptors recruit cellular signaling proteins, initiating signaling pathways. |
| brand: | | SIGMA |
| form: | | buffered aqueous glycerol solution |
| mdl_no: | | MFCD01867052 |
| name_suffix: | | ~80% (SDS-PAGE), recombinant, expressed in Escherichia coli, buffered aqueous glycerol solution |
| physical form: | | Solution in phosphate buffered saline containing 30% glycerol. |
| prod_type: | | Chemical |
| purity: | | ~80% (SDS-PAGE) |
| recombinant: | | expressed in Escherichia coli |
| s_codes: | | 23-24/25 |
| shipped in: | | dry ice |
| storage: | | -20C |
| storage temp: | | -20C |
| syns: | | HRG-beta |
| unspsc_code: | | 12352202 |
| wgk: | | 1 |
| more information: | | company product webpage |