| cat_no: | | E3641 |
| name: | | Epidermal Growth Factor Receptor human |
| gene id: | | human EGFR(1956) |
| link: | | www.sigmaaldrich.com/catalog/search ... |
| biochem/physiol actions: | | EGF exerts its actions by binding to the EGF receptor (EGFR), a 170 kDa glycoprotein having EGF-activated protein tyrosine kinase activity. Even in the absence of EGF-like ligands, EGFR can participate in cellular responses elicited by several other stimuli. High levels of EGFR are expressed in approximately one third of human epithelial tumors, and in the cancers of the bladder, breast or lung that have poor clinical prognosis, hence the interest in targeting EGFR. |
| brand: | | SIGMA |
| form: | | buffered aqueous glycerol solution |
| iod_codes: | | B |
| mdl_no: | | MFCD01634808 |
| name_suffix: | | buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry) |
| physical form: | | Solution in 50% glycerol, containing 50 mM HEPES, pH 7.6, 150 mM NaCl, 0.1% Triton and 1 mM dithiothreitol |
| prod_type: | | Chemical |
| shipped in: | | dry ice |
| storage: | | -70C |
| storage temp: | | -70C |
| syns: | | EGFR |
| unspsc_code: | | 12352202 |
| wgk: | | 1 |
| more information: | | company product webpage |
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