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| name: | Anti-Caspase 8 (GD-13) antibody produced in rabbit |
| cat_no: | C2976 |
| gene id: | human CASP8(841) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | IgG fraction of antiserum, buffered aqueous solution |
| storage temp.: | -20C |
| storage: | -20C |
| form: | buffered aqueous solution |
| physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide. |
| antibody form: | IgG fraction of antiserum |
| shipped in: | dry ice |
| species reactivity: | human |
| application(s): | microarray: suitable; immunoblotting: 1:1,000 using human Burkitt lymphoma Raji cell extract |
| immunogen: | synthetic peptide of the human caspase 8a/MACHalpha1 precursor (amino acids 362-374 with N-terminal added lysine), conjugated to KLH. |
| unspsc_code: | 12352203 |
| wgk: | 2 |
| mdl_no: | MFCD02095978 |
| mol wt: | antigen (caspase 8a) mol wt 55 kDa; antigen (caspase 8b) mol wt 54 kDa |
| specificity: | The sequence used as the immunogen corresponds to the C-terminal region of the enzyme p18 subunit and is identical in other human caspase 8 isoforms (MACHalpha2, MACHalpha3, MACHbeta) and has limited homology (approx. 50%) to mouse caspase 8. By immunoblotting, the antibody reacts with caspase 8a and caspase 8b. |
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more information: | company product webpage |