| request information: |
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| name: | Monoclonal Anti-Apolipoprotein E antibody produced in mouse |
| cat_no: | A8599 |
| gene id: | human APOE(348) |
| brand: | SIGMA |
| prod_type: | Chemical |
| name_suffix: | ~1 mg/mL, clone E6D7, purified immunoglobulin, buffered aqueous solution |
| storage temp.: | -20C |
| storage: | -20C |
| form: | buffered aqueous solution |
| physical form: | Solution in phosphate buffered saline. |
| antibody form: | purified immunoglobulin |
| shipped in: | dry ice |
| species reactivity: | human |
| application(s): | immunoprecipitation: suitable; indirect ELISA: suitable; immunoblotting: 1:102-1:103; immunohistochemistry: 1:100-1:10,000 using fixed tissues pretreated with 70% formic acid for 10-30 minutes at room temperature. |
| immunogen: | synthetic peptide spanning the polymorphic amino acid position 158 of ApoE. |
| syns: | Anti-Apo E |
| unspsc_code: | 12352203 |
| wgk: | 2 |
| mdl_no: | MFCD01864094 |
| clone: | E6D7 |
| isotype: | IgG1 |
| specificity: | Shown to enhance the risk for the development of Alzheimers's disease. Mutations in the APP gene in conjunction with the influence of ApoE appears to influence amyloid metabolism. Reacts to the E2, E3, and E4 isoforms of apoliporotein E. |
| concentration: | ~1 mg/mL |
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more information: | company product webpage |