| CatalogCode: | S-052-500 |
| ProductName: | beta NGF Antibody |
| Product Description: | Sheep Polyclonal anti-beta NGF |
| Clonality: | Polyclonal |
| Immunogen: | Native mouse beta NGF purified from submaxillary salivary gland (95% purity by PAGE) |
| Specificity: | A cross reactivity of less than 1% to recombinant human BDNF, NT3, NT4/5 by ELISA has been shown. |
| CrossReactivity: | This antiserum is known to cross react with mouse, rat, human and avian NGF bot not bovine NGF. |
| Packaging: | 0.5 mg |
| Uses: | IHC, 1-site ELISA, WB, immunoblot, inhibition of biological activity. A concentration of 1-3 µ/ml is recommended for IHC, western blot and immunoblot, ELISA, inhibition of biological activity in vitro. Use neat for in vivio studies at 2-10 µ/ml (ED50). This antiserum completely inhibits neuronal survival and the outgrowth actions of murine NGF in chicken DRG in vitro. The optimal working dilution should be determined by the end user. |
| Localization: | Accession Number: NGF_MOUSE |
| Background: | FUNCTION: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. SUBUNIT: Homodimer, associated by noncovalent forces. SUBCELLULAR LOCATION: Secreted protein. SIMILARITY: Belongs to the NGF-beta family. |
| ProductRef: | 1. Ebendal, T. et al (1989) J Neurosci Res 22, 223-240. ; 2. Zhou, X. F. et al (1994) J Neurosci Methods 54, 95-102. ; 3. Angeletti, P. U. et al (1968) Adv Enzymol Relat Areas Mol Biol 31, 51-75. |
| Purity: | Protein G purified IgG |
| Host_Name: | Sheep |
| Buffer: | Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. |
| ListPrice: | 275 |
| AppSummary: | IHC, WB, ELISA |
| ALTnames: | anti-Beta-nerve growth factor antibody |
| ProteinTarget: | beta NGF |
| PackageSize: | 0.5 mg |
| NotesMain: | This product is distributed for biosensis Pty Ltd, Australia. For the most up-to-date information regarding this product, please go to biosensis' website: http://www.biosensis.com/product_info.php?products_id=164 |
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