| Catalog Code: | R-114-100 |
| Product Type: | Primary Antibody |
| Product Name: | Parkin Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 5071 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-Parkin |
| Cross Reactivity: | This antibody is known to react with rat and human Parkin. |
| Species Summary: | Hu, Rt |
| Background: | Parkinson's disease is a common neurodegenerative disease with complex clinical features. Mutations in the gene, Parkin (PARK2), appear to be responsible for the pathogenesis of autosomal recessive juvenile Parkinsonism. Parkin plays a role in the ub |
| Alternate Names: | anti-Ubiquitin E3 ligase PRKN antibody, anti-Parkinson juvenile disease protein 2 antibody, anti-Parkinson disease protein 2. GENE NAME: PARK2 antibody, anti-PRKN antibody, biosensis |
| Immunogen: | A synthetic peptide (NSLIKELHHFRILGEE Q) as part of human Parkin conjugated to KLH |
| Localization: | Accession Number: PRKN2_HUMAN |
| Specificity: | This antiserum is known to be highly specific for Parkin shown by IHC and WB. |
| Buffer: | Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. |
| Packaging: | 0.1 ml Rabbit antisera. |
| Package Size: | 0.1 ml |
| Uses: | IHC, WB. A dilutioin of 1:1000 is recommended for immunohistochemistry and 1:2000 for western blot. Nice staining is achieved in neuronal and cytoplasmic granules sections treated with citrate buffer for antigen retrieval. Few inclusions are stained but t |
| Application Summary: | IHC, WB |
| Product References: | 1. Hottori et al. (1998) Biochem Biophys Res Commun. 249 (3): 754-758 ; 2. Kitada et al. (1998). Nature. 392: 605-608 ; 3. Kumru, H., et al., Ann. Neurol. 56(4):599-603 (2004). ; 4. Pigullo, S., et al., Parkinsonism Relat. Disord. 10(6):357-362 (2004). ; |
| Notes Main: | This product is distributed for biosensis Pty Ltd, Australia. For the most up-to-date information regarding this product, please go to biosensis' website: http://www.biosensis.com/product_info.php?products_id=189 |