| CatalogCode: | | PAB0620 |
| ProductName: | | STAT5A Antibody |
| Product Description: | | Rabbit Polyclonal anti-STAT5A - signal transducer and activator of transcription 5A [Ser726] |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S726 of human STAT5A. |
| CrossReactivity: | | Human. Other species not tested. |
| Packaging: | | 0.1 mg of rabbit IgG |
| Uses: | | This antibody is useful for Western Blot (Cell lysate), Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), ELISA. |
| Background: | | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. |
| Storage: | | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host_Name: | | Rabbit |
| ListPrice: | | 295 |
| AppSummary: | | WB, IHC-P, ELISA |
| SpeciesSummary: | | Hu |
| ALTnames: | | MGF antibody, anti-STAT5 |
| ProteinTarget: | | signal transducer and activator of transcription 5A |
| PackageSize: | | 0.1 mg |
| Phosphorylated: | | Ser726 |
| NotesMain: | | This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours.The immunizing protein is |
| Gene_Id: | | 6776 |
| Gene_Symbol: | | STAT5A |
| Ref_Sqnce: | | NP_003143; P42229 |
| Omim_ID: | | 601511 PAB0621 |
| more information: | | company product webpage |
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