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| Catalog Code: | PAB0578 |
| Product Name: | PTPN7 Phosphospecific Antibody |
| Product Description: | Rabbit Polyclonal anti-PTPN7 - protein tyrosine phosphatase, non-receptor type 7 [Ser246] |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 5778 |
| Gene Symbol: | PTPN7 |
| Reference Sequence: | NP_002823; P35236 |
| Omim ID: | 176889 |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S246 of human PTPN7. |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg of rabbit IgG |
| Uses: | This antibody is useful for ELISA, Dot Blot (peptide). |
| Background: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host Name: | Rabbit |
| Application Summary: | ELISA, Dot Blot |
| Species Summary: | Hu |
| Alternate Names: | anti-BPTP-4 antibody, anti-HEPTP antibody, anti-LC-PTP antibody, anti-LPTP antibody, anti-PTPNI antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% sodium azide. |
| Phosphorylated: | Ser246 |
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more information: | company product webpage |