| CatalogCode: | PAB0573 |
| ProductName: | PDGFRB Antibody |
| Product Description: | Rabbit Polyclonal anti-PDGFRB - platelet-derived growth factor receptor, beta polypeptide [Tyr579] |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y579 of human PDGFRB. |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg of rabbit IgG |
| Uses: | This antibody is useful for Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), ELISA. |
| Background: | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
| Storage: | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host_Name: | Rabbit |
| ListPrice: | 295 |
| AppSummary: | IHC-P, ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | CD140B antibody, anti-JTK12 antibody, anti-PDGF-R-beta antibody, anti-PDGFR antibody, anti-PDGFR1 |
| ProteinTarget: | platelet-derived growth factor receptor, beta polypeptide |
| PackageSize: | 0.1 mg |
| Phosphorylated: | Tyr579 |
| NotesMain: | This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours.The immunizing protein is |
| Gene_Id: | 5159 |
| Gene_Symbol: | PDGFRB |
| Ref_Sqnce: | NP_002600; P09619 |
| Omim_ID: | 173410 H00005159-B01 |