| request information: |
|
| Catalog Code: | PAB0545 |
| Product Name: | NFKB1 Phosphospecific Antibody |
| Product Description: | Rabbit Polyclonal anti-NFKB1 - nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) [Ser893] |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 4790 |
| Gene Symbol: | NFKB1 |
| Reference Sequence: | NP_003989; P19838 |
| Omim ID: | 164011 |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S893 of human NFKB1. |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg of rabbit IgG |
| Uses: | This antibody is useful for ELISA, Dot Blot (peptide). |
| Background: | This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. |
| Storage: | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host Name: | Rabbit |
| Application Summary: | ELISA, Dot Blot |
| Species Summary: | Hu |
| Alternate Names: | antiDKFZp686C01211 antibody, anti-EBP-1 antibody, anti-KBF1 antibody, anti-MGC54151 antibody, anti-NF-kappa-B antibody, anti-NFKB-p105 antibody, anti-NFKB-p50 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% sodium azide. |
| Phosphorylated: | Ser893 |
order or
more information: | company product webpage |