| CatalogCode: | | PAB0511 |
| ProductName: | | MAP2K4 Antibody |
| Product Description: | | Rabbit Polyclonal anti-MAP2K4 - mitogen-activated protein kinase kinase 4 [Ser80] |
| Clonality: | | Polyclonal |
| Immunogen: | | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S80 of human MAP2K4. |
| CrossReactivity: | | Human. Other species not tested. |
| Packaging: | | 0.1 mg of rabbit IgG |
| Uses: | | This antibody is useful for ELISA, Dot Blot (peptide). |
| Background: | | This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. |
| Storage: | | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host_Name: | | Rabbit |
| ListPrice: | | 295 |
| AppSummary: | | ELISA, DB |
| SpeciesSummary: | | Hu |
| ALTnames: | | JNKK antibody, anti-JNKK1 antibody, anti-MAPKK4 antibody, anti-MEK4 antibody, anti-MKK4 antibody, anti-PRKMK4 antibody, anti-SEK1 antibody, anti-SERK1 |
| ProteinTarget: | | mitogen-activated protein kinase kinase 4 |
| PackageSize: | | 0.1 mg |
| Phosphorylated: | | Ser80 |
| NotesMain: | | This antibody is available only in North America and is supplied by Abnova If in stock in Taiwan. delivery is 10-14 days. If not in stock. lead times can be extended. We will inform you of any extended delays within 48 hours.The immunizing protein is |
| Gene_Id: | | 6416 |
| Gene_Symbol: | | MAP2K4 |
| Ref_Sqnce: | | NP_003001; P45985 |
| Omim_ID: | | 601335 PAB0531 |
| more information: | | company product webpage |