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| Catalog Code: | PAB0427 |
| Product Name: | CDC25A Phosphospecific Antibody |
| Product Description: | Rabbit Polyclonal anti-CDC25A - cell division cycle 25 homolog A (S. pombe) [Ser278] |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 993 |
| Gene Symbol: | CDC25A |
| Reference Sequence: | NP_001780; P30304 |
| Omim ID: | 116947 |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S278 of human CDC25A. |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg of rabbit IgG |
| Uses: | This antibody is useful for Western Blot (Tissue lysate), Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), ELISA. |
| Background: | CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host Name: | Rabbit |
| Application Summary: | Western Blot, Immunohistochemistry-Paraffin, ELISA |
| Species Summary: | Hu |
| Alternate Names: | anti-RP11-265F14.3 antibody, anti-APAF-3 antibody, anti-APAF3 antibody, anti-CASPASE-9c antibody, anti-ICE-LAP6 antibody, anti-MCH6 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% sodium azide. |
| Phosphorylated: | Ser278 |
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more information: | company product webpage |