| request information: |
|
| Catalog Code: | PAB0395 |
| Product Name: | YWHAE Phosphospecific Antibody |
| Product Description: | Rabbit Polyclonal anti-YWHAE - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide [Thr232] |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 7531 |
| Gene Symbol: | YWHAE |
| Reference Sequence: | NP_006752; P62258 |
| Omim ID: | 605066 |
| Immunogen: | Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T232 of human YWHAE. |
| Cross Reactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg of rabbit IgG |
| Uses: | This antibody is useful for Western Blot (Tissue lysate), Western Blot (Cell lysate), Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), ELISA. |
| Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. |
| Storage: | Store at +4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Host Name: | Rabbit |
| Application Summary: | Western Blot, Western Blot, Immunohistochemistry-Paraffin, ELISA |
| Species Summary: | Hu |
| Alternate Names: | anti-14-3-3E antibody, anti-FLJ45465 antibody, anti-KCIP-1 antibody, anti-MDCR antibody, anti-MDS antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% sodium azide. |
| Phosphorylated: | Thr232 |
order or
more information: | company product webpage |