| Catalog Code: | NSB870 |
| Product Type: | Primary Antibody |
| Product Name: | Integrin beta 1 Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 3688 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Integrin beta 1 [Ser785] |
| Phosphorylated: | Ser785 |
| Cross Reactivity: | Cross-reacts with Chicken, Human and Mouse. Expected to cross-react with Rat (100% identity with immunogen) and a wide range of other species due to sequence homology. Not yet tested in other species. |
| Species Summary: | Ch, Hu, Mu |
| Alternate Names: | anti-beta 1 subunit antibody, anti-CD29 antigen antibody, anti-Fibrinogen Receptor beta subunit antibody, anti-GPIIA antibody, anti-ITGB1 antibody, anti-MDF2 antibody, anti-Very Late Activation Protein beta Polypeptide antibody, anti-VLAB antibody, anti-V |
| Immunogen: | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human Integrin beta 1. This sequence is conserved among many species including mouse, rat and chicken. |
| Specificity: | Integrin beta 2 (55% identity) and Integrin beta 7 (64% identity) have also not been tested, but are not expected to react. |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: PBS, 1mg/ml BSA (IgG, protease free). pH 7.3 |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Concentration: | 0.5 mg/ml |
| Uses: | WB: Use at a concentration of 0.1-1.0 ug/ml. Predicted molecular weight: 130 kDa. ICC: Use at a dilution of 1/5,000. IF: Use at a dilution of 1/200-1/1,000. IHC-Fr: Use at a dilution of 1/200-1/1,000. Not tested in other applications. Optimal dilutions/co |
| Application Summary: | WB |
| General References: | General / background references:Mulrooney JP et al. Serine 785 phosphorylation of the beta1 cytoplasmic domain modulates beta1A-integrin-dependent functions. J Cell Sci 114:2525-33 (2001). Schlaepfer DD et al. Signaling through focal adhe |