| Catalog Code: | NSB836 |
| Product Type: | Primary Antibody |
| Product Name: | PED Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 4948 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-PED [Ser116] |
| Phosphorylated: | Ser116 |
| Cross Reactivity: | Human and mouse (100% homologous) PED/PEA-15. Rat PED/PEA-15 (100% homologous) has not been tested, but is expected to react. |
| Species Summary: | Hu, Mu |
| Background: | PED/PEA-15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes - 15 kDa) is a widely expressed 15 kDa protein comprised of an N-terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, |
| Alternate Names: | anti-HMAT1 antibody, anti-HUMMAT1H antibody, anti-MAT1 antibody, anti-MAT1H antibody, anti-PEA 15 antibody, anti-PED antibody |
| Immunogen: | The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PED/PEA-15 that contains serine 116. The sequence is conserved in mouse and rat. |
| Packaging: | 0.1 ml of epitope-affinity purified rabbit antisera in PBS, pH 7.4 (without Mg2+ and Ca2+), pH 7.3 (+/- 0.1), 50% glycerol, with 1.0 mg/mL BSA (IgG, protease free) as a carrier. Contains 0.02% sodium azide (Caution: sodium azide is a poisonous and hazardo |
| Package Size: | 0.1 ml |
| Uses: | This antibody is suitable for use in Western blotting. The recommended concentration for use in Western blotting is 1:1,000. *The optimal concentration should be determined for each specific application. |
| Application Summary: | WB |
| General References: | Renault, F., et al. (2003) The multifunctional protein PEA-15 is involved in the control of apoptosis and cell cycle in astrocytes. Biochem. Pharmacol. 66(8):1581-1588. Chou, F.L., et al. (2003) PEA-15 binding to ERK1/2 MAP Kinases is required for its mod |