| Catalog Code: | NSB800 |
| Product Type: | Primary Antibody |
| Product Name: | Insulin Receptor Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 3643 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Insulin Receptor [Tyr972] |
| Phosphorylated: | Tyr972 |
| Cross Reactivity: | Cross-reacts with Human and Mouse. There is 100% homology with rat. Not yet tested in other species. |
| Species Summary: | Hu, Mu |
| Background: | Biological actions of insulin are mediated by the Insulin Receptor (IR), a receptor tyrosine kinase that regulates multiple signaling pathways through activation of a series of phosphorylation cascades. The IR is a heterotetrameric protein consisting of t |
| Alternate Names: | anti-IGFR1 antibody, anti-Insulin growth factor 1 receptor antibody, anti-CD221 antibody |
| Immunogen: | Synthetic phosphopeptide derived from the region of the human Insulin Receptor that contains tyrosine 972. |
| Localization: | Plasma membrane |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: 0.1% BSA, PBS. pH 7.4 |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Concentration: | 0.5 mg/ml |
| Uses: | WB: Use a dilution of 1:1000. Detects a band of approximately 110 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | WB |
| General References: | General / background references:Bevan P Insulin signalling. J Cell Sci 114:1429-30 (2001). Skorey KI et al. Development of a robust scintillation proximity assay for protein tyrosine phosphatase 1B using the catalytically inactive (C215S) |