| Catalog Code: | NSB668 |
| Product Type: | Primary Antibody |
| Product Name: | PKR Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 5610 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-PKR [Thr451] |
| Phosphorylated: | Thr451 |
| Cross Reactivity: | Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Species Summary: | Hu, Mu |
| Background: | PKR is an interferon-inducible serine/threonine-specific proteinkinase. It is widely expressed in eukaryotic organisms and activated by double-stranded RNA. The activation of PKR is accompanied by autophosphorylation at multiple sites. Phosphorylation of |
| Alternate Names: | anti-Double Stranded RNA Activated Interferon Inducible Protein Kinase antibody, anti-EIF2AK1 antibody, anti-Interferon inducible elF2 alpha kinase antibody, anti-P1/eIF2A protein kinase antibody, anti-p68 kinase antibody, anti-PRKR antibody |
| Immunogen: | Synthetic peptide derived from the region of PKR that contains threonine451. The sequence was aligned to human. |
| Specificity: | Phosphorylation site-specific antibody selective for the phosphorylated form of the PKR (double-stranded RNA-dependent protein kinase) protein containing a phosphate on threonine 451. This antibody recognizes a protein of 65-68 kDa resolved by SDS-PAGE, i |
| Purity: | Immunogen affinity purified |
| Buffer: | Constituents: 50% Glycerol, 0.1% BSA, 20mM Sodium Phosphate, 10mM So |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Uses: | WB: Use at a dilution of 1/1000. Predicted molecular weight: 67 kDa. |
| Application Summary: | WB |
| General References: | This product has been used in:Pataer A et al. Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR). Cancer Res 62:22 |