| Catalog Code: | NSB625 |
| Product Type: | Primary Antibody |
| Product Name: | Focal Adhesion Kinase Antibody |
| List Price: | 310 |
| Clonality: | Monoclonal |
| Gene ID: | 5747 |
| Host: | Rabbit |
| Clone: | 141-9 |
| Isotype: | IgG |
| Product Description: | Rabbit Monoclonal anti-Focal Adhesion Kinase (141-9) [Tyr397] |
| Phosphorylated: | Tyr397 |
| Cross Reactivity: | Cross-reacts with Human. Expected to cross-react with Mouse Drosophilia melanogaster and Xenopus laevis. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | Focal Adhesion Kinase is a 125 kDa non-receptor protein tyrosine kinase that was discovered as a substrate for Src, and is a key element of integrin signaling. Focal Adhesion Kinase plays a central role in cell spreading, differentiation, migration, cell |
| Immunogen: | Synthetic peptide derived from the region of Focal Adhesion Kinase that contains tyrosine 397. The sequence is conserved in human, mouse, rat, chicken and frog. |
| Purity: | Protein A purified |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: 50% Glycerol, PBS, 1mg/ml BSA (IgG, protease free). pH |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Uses: | ICC: starting diultion of 1/50. WB: starting dilution of 1/1000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | ICC, WB |
| General References: | Cao, Y., et al. (2005) Growth factors stimulate kidney proximal tubule cell migration independent of augmented tyrosine phosphorylation of focal adhesion kinase. Biochem. Biophys. Res. Com. 328:560-566.Sekimoto, H., et al. (2005) |