| CatalogCode: | NSB524 |
| ProductName: | Bad Antibody |
| Product Description: | Rabbit Polyclonal anti-Bad [Ser136] |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide (Human) derived from the region of Bad that contains serine 136, based on the Homo sapiens sequence. This region is identical among many species including rat and mouse. |
| Specificity: | This antibody recognizes Bad (MW 23 kDa) only when phosphorylated at serine 136. |
| CrossReactivity: | Cross-reacts with Human.Expected to cross-react with Mouse, Rat and a wide range of species due to sequence homology.Not yet tested in other species. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | WB: Predicted molecular weight: 23 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Mitochondrial |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Constituents: PBS, 1mg/ml BSA. pH 7.3 |
| ListPrice: | 310 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Bcl-2 binding component 6 antibody; anti-BBC 2 antibody; anti-BBC2 antibody; anti-BBC6 antibody; anti-Bcl 2 Antagonist of Cell Death antibody; anti-Bcl 2 Binding Component 6 antibody; anti-BCL X / BCL 2 Binding Protein antibody; anti-BCL X Binding Protein antibody; anti-Bcl XL/Bcl 2 Associated Death Promoter antibody; anti-Bcl2 Associated Death Promoter antibody; anti-Bcl2 Like 8 Protein antibody; anti-BCL2L8 antibody; anti-BclXL antibody; anti-Proapoptotic BH3 Only Protein antibody |
| ProteinTarget: | Bad phospho |
| PackageSize: | 0.1 ml |
| GeneralRef: | General / background references:Noshita N et al. Akt phosphorylation and neuronal survival after traumatic brain injury in mice. Neurobiol Dis 9:294-304 (2002). Neshat MS et al. The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf. Mol Cell Biol 20:1179-86 (2000). del Peso L et al. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-9 (1997). |
| Phosphorylated: | Ser136 |