| Catalog Code: | NSB426 |
| Product Type: | Primary Antibody |
| Product Name: | JAK2 Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 3717 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-JAK2 [Tyr1007/Tyr1008] |
| Phosphorylated: | Tyr1007/Tyr1008 |
| Cross Reactivity: | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. |
| Species Summary: | Hu, Mu, Rt |
| Background: | Janus Kinase 2 (JAK 2) is a 130 kDa tyrosine kinase involved in cytoplasmic signal transduction. Ligand binding to a variety of cell surface receptors (e.g., cytokine, growth factor, GPCRs) leads to an association of those receptors with JAK proteins, whi |
| Alternate Names: | anti-JAK-2 antibody, anti-JAK 2 antibody, anti-Janus Kinase 2 antibody |
| Immunogen: | Synthetic phospho peptide (Human). |
| Purity: | Immunogen affinity purified |
| Buffer: | Dulbeccos PBS containing 50% glycerol with 1.0 mg/mL BSA and 0.05% Sodium Azide |
| Packaging: | 0.1 mg AP antisera. |
| Package Size: | 0.1 ml |
| Uses: | This antibody can be used in Western Blot where a 130 kDa band is deteted. Recommended Starting Dilutions*: WB: 1/1000 *Optimal dilutions should be determined by the end user. |
| Application Summary: | WB |
| Product References: | Kirito K et al. Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways. J Biol Chem 277:8329-37 (2002). Shaw S et al. Janus kinase 2, an early target of alpha 7 nicotinic acetyl |