| Catalog Code: | NSB232 |
| Product Type: | Primary Antibody |
| Product Name: | ZAP70 Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 7535 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-ZAP70 [Tyr315/Tyr319] |
| Phosphorylated: | Tyr315/Tyr319 |
| Cross Reactivity: | Cross-reacts with Human.Expected to cross-react with Mouse due to sequence homology.Not yet tested in other species. |
| Species Summary: | Hu |
| Alternate Names: | anti-70 kDa zeta associated protein antibody, anti-Selective T cell defect antibody, anti-SRK antibody, anti-STD antibody, anti-Syk related tyrosine kinase antibody, anti-Truncated ZAP kinase antibody, anti-Tyrosine protein kinase ZAP70 antibody, anti-TZK |
| Immunogen: | Synthetic peptide derived from the region of human ZAP70 that contains tyrosines 315 and 319 (unfortunately, the amino acid sequence is considered to be commercially sensitive) |
| Localization: | Cytoplasmic |
| Specificity: | Syk (85% homologous) may cross react in some cell systems. |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: Dulbecco's PBS without magnesium and calcium, 50% Glyc |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Uses: | WB: Use at a dilution of 1/1000. Predicted molecular weight: 74.3 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | WB |
| General References: | General / background references:Orchard JA et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 363:105-11 (2004). Sakaguchi N et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes a |
| Notes Main: | Centrifuge before opening to settle contents. |