| Catalog Code: | NSB200 |
| Product Type: | Primary Antibody |
| Product Name: | Arrestin beta 1 Antibody |
| List Price: | 310 |
| Clonality: | Polyclonal |
| Gene ID: | 408 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Arrestin beta 1 [Ser412] |
| Phosphorylated: | Ser412 |
| Cross Reactivity: | Cross-reacts with Mouse and Rat. Expected to cross-react with Cow (77% identity with immunogen) and Human (77% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Species Summary: | Mu, Rt |
| Background: | Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent des |
| Immunogen: | Synthetic phospho peptide (Rat) derived from theregion of beta Arrestin 1 that contains Ser 412. |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: PBS, 1mg/ml BSA. pH 7.3 |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Concentration: | 0.75 mg/ml |
| Uses: | WB: Use at a concentration of 0.1 - 1 ug/ml. Detects a band of approximately 55 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | WB |
| General References: | General / background references:Tohgo A et al. beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J Biol Chem 277:9429-36 (2002). |