| CatalogCode: | NLS998 |
| ProductName: | Somatostatin Receptor Type 2 Antibody |
| Product Description: | Rabbit Polyclonal anti-Somatostatin Receptor Type 2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide [KLH conjugated] made to the 2nd extracellular loop |
| CrossReactivity: | Human. There is 100 % rat identity and 100 % rat homology. There is 100 % mouse identity and 100 % mouse homology. |
| Packaging: | 0.05 ml Immunogen affinity purified Rabbit antisera. |
| Localization: | Cell Membrane |
| Background: | SST2 is a Somatostatin receptor. Somatostatin negatively regulates the growth of various normal and tumour cells via five somatostatin receptors. Somatostatin receptors are expressed by a large variety of human tumors, and the predominant expression of SST2 receptors in tumor tissues forms the basis for the successful application of SST2-preferring agonists in the treatment of patients with GH-secreting pituitary adenomas, as well as in patients with carcinoid or islet cell tumors. The SST2 receptor exists as two splice variants that differ in length and composition of their intracellular carboxy termini. SST2 is the only member of the somatostatin receptor family that contains introns. SST2 expression has been reported in adrenal, aorta, brain, breast, eye, gastrointestinal tract, pancreas, prostate, spinal cord, and thyroid. ESTs have been isolated from brain, eye, head/neck, kidney, lymph node, pineal, and prostate libraries. |
| Storage: | Store at 4C short term. Aliquot and store at -70C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, PH 7.7 |
| ListPrice: | 375 |
| AppSummary: | WB, IHC-P |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-SSTR2 antibody; anti-Somatostatin Receptor 2 antibody |
| ProteinTarget: | Somatostatin Receptor Type 2 |
| PackageSize: | 0.05 ml |
| NotesMain: | Genbank accession number: NM_001050 |
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